Combined Enteral And Parenteral Nutritional Support In Patients With Severe Craniocerebral Injury In The Timing Of Application

Objective：( PN+EN ) by combined enteral and parenteral nutrition support in patients with severehead injury with different time application, contrast in patients with serum CRP, IgG, IgMcontent and GCS score changes and systemic inflammatory response syndrome ( SIRS )incidence of different, combined enteral and parenteral nutritional support in patients withheavy craniocerebral injury in application of optimal timing select, highlight the early fullenteral nutrition in patients with severe craniocerebral injury and its clinical significance inapplication.Will meet the inclusion criteria in 58 patients of Department of neurosurgery in patientswith severe head injury as the research object, according to by parenteral complete transition toenteral nutrition in different time were divided into 2 groups, group A ( less than 5 days tocomplete the transition of patients ) and group B ( >5 days to complete the transition ofpatients ),28 cases in group A, B group of 30 cases. Incorporating patient gender, age, illness, inGCS score and the operation time and operation mode are statistically, no statisticalsignificance ( P >0.05), with comparable. All patients admitted to24h were given parenteralnutrition,24h observed in patients with indwelling gastric retention rate≤150ml, is givencombined with enteral nutrition. From two patients admitted to24h group ( i.e. before treatment)and tenth days of hospitalization ( i.e. after treatment, serum, respectively ) on the serum CRP,IgG, IgM were determined, and the two groups before treatment, the scores of GCS werecompared, and in two groups after the treatment the incidence of SIRS is different than, usingthe SPSS13.0 statistical software package for the two groups before and after the results of thestatistical analysis of relevant indicators, the situation changes, the changes and its clinicalsignificance.Results：1.The Changes in the serum levels of CRP in two groups Serum CRP levels significantlyincrease in each group of patients admitted within 24h, But there was no significant difference（P>0.05）；After two sets of nutritional therapy, with Changes over time, Serum levels of CRPconcentrations showed a downward trend. The serum CRP levels of the third day of thesequential treatment significantly lower than the first five days of the sequential group, Thedifference was statistically significant（P<0.05）。2.the change of Two groups of patients with serum IgG, IgM content The serum IgG, IgM levels were decreased in hospitalized 24h Within two groups of patients, by Contrasting but nostatistical significance（P >0.05）；The content of IgG in the serum of IgM t Compared with theprevious rise, the more significant increasedwas the third days of the sequential grou（pP<0.05）;the sequential of the fifth days group was no significant difference（P >0.05）.3．Two groups of patients combined enteral and parenteral nutrition after treatment withGCS score changes, in two groups of patients were improved state of consciousness, in which Agroup than in B group were significantly improved.4. Two groups of patients after treatment of SIRS comparisons of incidence rates, twogroups of patients after active treatment, group A in patients with systemic inflammatoryresponse syndrome ( SIRS ) incidence was lower than that of B group.Conclusion：By contrast, in patients with severe head injury positive early full enteral nutrition supporttreatment of significant clinical effect, helps to relieve patients with systemic inflammatoryresponse, strengthen immunity, improve the patient ’s state of consciousness, good for therecovery of the patients.