The Analysis Of Related Factors Of Ectopic Pregnancy After IVF-ET

Research Purposeectopic pregnancy in IVF and ICSI-ET cycle compared with intrauterine pregnancy related information of the general situation of two groups of patients, treatment, and embryo transfer, etc., to find out the impact of IVF/ICSI cycle, ectopic pregnancy-related factors, to guide clinical improvement IVF/ICSI cycle pregnancy outcome. Material and MethodA retrospective analysis from January2009to December2010, Guangxi Medical University First Affiliated Hospital, Center of Reproduction. IVF cycles and ICSI cycles after treatment, patients received clinical pregnancy clinical data, a total of496pregnancy cycle, which of IVF-ET396cycles,79.82%of the total pregnancy, intrauterine pregnancy (n=361), the EP35cases; fresh of ICSI-ET in100cycles, accounting for20.18%of the pregnancy, intrauterine pregnancy93cases, the EP7cases. Comparative analysis on the group of IVF and ICSI cycles of intrauterine pregnancy and ectopic pregnancy group, intrauterine pregnancy as the control group, ectopic pregnancy as the experimental group.Select patients with both luteal phase long protocol ovulation induction drug of choice for urinary gonadotropin (Group Cabernet Franc Cabernet Franc Pharmaceutical Factory) and of Gonadotropin selection Gonalf(Swiss company Serono). Regular B-ultrasound monitoring follicle growth and development,2-3follicular development diameter greater than18mm, the night injection HCG10000u,34-36hours after oocyte retrieval, insemination way according to sperm quality decision to choose IVF/ICSI to observe embryonic development and the third day after ovulation and embryo transfer. Outpatient follow-up in patients with pregnancy, track record and analyze the general situation of the two groups of patients, treatment and transplant.Statistical choose SPSS13.0software processing system, were compared by T test, different treatment factors on the number of analysis of variance, describes the relationship of each predictor of pregnancy outcome using non-conditional Logistic regression analysis, set two-sided test, p<0.05was considered statistically significant.Results1.The single factor analysisCompare the IVF cycle and ICSI cycles the experimental group and control group, male/woman’s age, infertility duration, body mass index AFC, basis of FSH (bBSH) the value of the above indicators was no significant difference, p values>0.05.Compare the IVF cycles and ICSI cycles of the experimental group and control group, infertility diagnosis, the flow of history, history of ectopic pregnancy, history of pelvic surgery, tubal factor infertility, with or without the merger endometriosis, whether the merger of PCOS, which IVF cycle history of ectopic pregnancy and tubal factor infertility, p-value less than0.05, the difference was statistically significant. ICSI cycle, the above indicators were not statistically significant, p values>0.05.IVF cycle and ICSI cycles of the experimental group and control group Da Feilin dose of Gn days of Gn total dose of HCG day Em of HCG day E2, ET day Em, where Gn the total use of IVF and ICSI cycles p-value<0.05, the difference was statistically significant, the rest of the p-value>0.05, no statistically significant difference.Eggs and embryos of IVF cycles and ICSI cycles of intrauterine pregnancy group and the ectopic pregnancy group was to include the number of oocytes, quality embryos, fertilization rate, cleavage rate, excellent embryo rate, Was no significant difference, p>0.05Experimental and control groups of IVF cycles and ICSI cycles transplantation, including the inner tube from the uterine cavity at the bottom of the distance (mm), gas images from the uterine cavity at the bottom of the distance (mm),with or without using the cervical clamp, number of embryos transferred, gas image distance from the IVF and ICSI cycles of the uterine cavity at the bottom of p-value<0.05, the difference was statistically significant, the remaining were not statistically significant.2, Multi-factor analysisUnivariate analysis of the differences statistically significant four factors:a history of ectopic pregnancy, tubal factor infertility, the total use of Gn, gas image from the distance of the uterine cavity at the bottom of the multivariate logistic regression analysis, results show that ectopic ectopic pregnancy after pregnancy history and tubal factor infertility significant effect on IVF-ET outcome.The gas images between the two groups from the uterine cavity at the bottom of the distance grouping, a group of10-15mm, a group of16-20mm, the difference between the two groups, the results show that10-15mm group difference was statistically significant.Conclusion1. Tubal factors are risk factors for ectopic pregnancy after IVF-ET.2. Increased risk of ectopic pregnancy of the history of ectopic pregnancy patients after IVF-ET.3. The total application amount of Gn will probably affect the occurrence of the ectopic pregnancy in IVF-ET.4. Embryo to be placed in the uterine position will probably affect the occurrence of the ectopic pregnancy in IVF-ET.