An Analysis On The Causative Factors Of Clinical Symptoms In Patients With Irritable Bowel Syndrome

OBJECTIVE: To explore the potential causative factors of clinical symptoms inpatients with irritable bowel syndrome(IBS).METHODS: A total of276IBS out-patients based on the RomeⅢ criteria,whichpresented to the gastroenterological clinic were enrolled in this questionnaire.RESULTS:1、The276IBS patients included126male(45.65%) and150female (54.35%) withmean age of42.66±11.93years old, and34.78%patients were41-50years old.2、Two hundred and nineteen patients (79.35%) reported that some foods may causetheir IBS-symptom onset, such as spicy foods(34.06%), overnight/stale foods(32.25%), dairy products (29.71%), and bean products (23.55%).147patients(53.26%) were affected by several certain foods.3、One hundred and thirty-eight patients(50.00%) reported that their IBS-symtomrecurrence was associated with intake of some drinks, such as alcohol(27.54%) andcold water(25.00%).63patients (22.83%) were affected by several drinks.4、One hundred and fourteen patients (41.30%) reported that the symptom recurrencewas associated with season/weather, especially at seasonal alternate.5、Thirty-three famale patients(22.00%) reported that the symptom recurrence wasassociated with menstruation, mainly in premenstrual phase(12.00%) and menstrualperiod (9.33%).6、One hundred and sixteen patients(42.65%) had sleep disturbance.CONCLUSION: The recurrence of IBS symptoms may associate with some certainfoods (such as spicy foods, overnight/stale foods, dairy products and bean products),drinks (such as alcohol and cold water), season/weather (such as seasonal alternate),menstrual cycle and sleep disturbance. and the avoidance of the potential causativefactors may reduce the symptom onset in patients with IBS.