Microwave Synthesis Of Fluorescent Quantum Dots And Silicon Nanowires For In Vivo And In Vitro Imaging

Quantum dots (QDs) possess unique optical properties, Therefore, QDs, which areconsidered as the novel fluorescent probes, have elicited a great deal of attentions in thepast decade. In this thesis, microwave-assissted synthetic strategies are developed forpreparation of fluorescent and water-dispersed quantum dots (QDs) and siliconnanowires (SiNWs), which are further utilized for bioimaging applications. The detailsare as follows:(1) The high quality near-infrared-emitting quantum dots (NIR QDs) are directlysynthesized in aqueous phase through a facile one-step microwave-assisted method.Efficient tumor passive targeting in live mice was shown by using the prepared QDs.(2) We present a new microwave-assisted method for one-pot synthesis ofwater-dispersible silicon quantum dots (SiQDs). the resultant SiQDs are promisingbiological probes for long-term and real-time immunofluorescent cellularimaging.These researches provided useful evidence for further nano-biologicalapplications of quantum dots as fluorescent probes.(3) We present a novel kind of multicolor QD-decorated SiNWs,which are directlyprepared in the aqueous phase by a facile one-pot strategy assisted by microwaveirradiation. And they are well-suited to long-term and real-time immunofluorescentcellular imaging.