Design Of Visual Experimental Platform Based On Optical Imaging And Microelectrode Array

The visual system is the most important pathway for human and mammal to communicate with the world. However, we know little about the visual-processing mechanism because it is very complex in human brain.As a preparative work for the study of visual system, this paper focused on the design and construction of the visual experimental platform based on optical imaging and microelectrode array technology. This work which is related to the hardware and software is the foundation of next study in visual system.Firstly, through widely reading, the actuality of this field is reviewed, and the physiology basis for the visual system is introduced briefly. Secondly, the author designed the whole hardware system of the visual experimental platform on conditions of our laboratory. Then, the system for data acquisition which is based on the optical imaging and microelectrode array is constructed. At the same time, we built the visual stimulate system to stimulate animals and the monitoring system to stabilize life state. Then, a program is advanced to make data acquisition system synchronize with stimulate system . Thirdly, with the help of the toolbox of Cambridge Research System, some programs are written to generate special figure which are used to stimulate the animal. Those programs are designed to meet the need of the study for primary visual cortex. An artery-vein separation method which is based on vessel extracted method, ICA and clustering is proposed as the preprocessing of OI data. Finally, directions and targets for the further work about the research on visual system are suggested.