Objective:In this study, by retrospective study of three database of functional dyspepsia of TCM literature and the objective research of Stagnation gastrointestinal hormones in the liver temper,Understands the functionality dyspepsia existing card distributed rule,By Elisa test liver temper sluggish card gastrointestinal hormones CCK, VIP,To further understanding of the pathogenesis of functional dyspepsia and correlation of CCK, VIP, guiding the diagnosis and treatment of functional dyspepsia.Methods:1.Retrospective study:Through the VIP, ten thousand party, Tsinghua tong fang three big database,input keywords functionality dyspepsia card distribution discusses dialectically governs the Chinese medicine treatment cooperation of Chinese and Western medicine treatment dialectical minute, separately from three big databases the search and the functionality dyspepsia card distribution related literature, counts functionality dyspepsia all cards, presents the frequency according to it, summarizes the functionality dyspepsia distributed rule.2.Objective research:Collected from March2011to March2012, received treatment in Guiyang City Hospital of Traditional Chinese Medicine, Chinese Medicine Hospital of Hunan Province, Zhang jiajie City Hospital and in accordance with functional dyspepsia liver temper stagnation syndrome cases,30cases, Normal control group10cases,from the various subjects under fasting remove the blood4ml in a test tube containing50μ110%of EDTA disodium and50μ1aprotinin immediately after blood mix. Kept at low temperature specimens.Centrifugal separation of plasma conducted Elisa detection and determination in strict accordance with the manual method. Select the gastrointestinal hormone CCK and VIP two indicators for the determination of the targetResult:1Functional dyspepsia TCM syndrome distribution,Collected from the three database,the present functionality dyspepsia Chinese medicine card altogether has47cards, appears frequency highest of five TCM card types respectively are:spleen and stomach weak card,liver-stomach disharmony card,spleen and stomach damp-heat card,The Stagnated Heat Syndrome in the Liver and Stomachs Diet stagnant card。Its frequency of occurrence, respectively45.57%,40.08%,36.71%,32.49%,29.96%。2Functional dyspepsia liver temper Stagnation CCK,VIP, this two gastrointestinal hormones increased significantly higher than normal Conclusion:1.Weakness of spleen and stomach, liver-stomach disharmony, taste hot and damp,these three cards are the most cards in the Functional dyspepsia TCM syndrome distribution,Three cards occupy all functionality dyspepsia Chinese medicine card38.75%, and its distribution is not related with the gender and area, Along with the age growth, the weakness of spleen and stomach card disease incidence rate elevates gradually.2.CCK(cholecystokinin) and VIP(vasoactive intestinal peptide) in the stagnation of liver temper of Functional dyspepsia increase compared with normal subjects are different significantly. The two may be one of the pathological basis of functional dyspepsia liver temper the incidence of Stagnation. |