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Chronic Kinbel Failure Of Spleen And Deficiency And Damp Turbidny Stasis In Patients With TGF-β1, HGF Expression Differences On Discuss

Posted on:2013-01-15Degree:MasterType:Thesis
Country:ChinaCandidate:R N AoFull Text:PDF
GTID:2214330374467317Subject:Chinese medical science
Abstract/Summary:PDF Full Text Request
Objective: The present study based on the theory of Chinesemedicine,combined with modern research methods,observation of theimaginary,spirical and renal fibrosis related relationship betweencytokines,thereby providing objective syndromedifferentiation,standardization provides certain theory basis.Methods: Take in the virtual,empirical patients of all36cases and20cases of normal control group,collected fasting blood and urinaryretention samples,centrifugal.Application of enzyme linkedimmunosorbent assay specinmens TGF-β1, HGF sample concentration.Results:Evidence of serum and urine of TGF-β1expression moredeficiency and control groups increased; the expression of HGF isdeficiency group and the control group increased significantly.Deficiency of serum and urine of HGF expression reduced comparedwith the empirical group, rather than the control group. TGF-β1islower than the empirical group, compared with the control groupincreased.Conclusion:Positive group of chronic renal failure, renal fibrosis,the fibrogenic cytokines increased expression of the antifibrotic cytokine expression does not reduce. Deficiency group of anti-fibrogeniccytokines expression does not reduce, fibrogenic cytokines expressionwas increased.
Keywords/Search Tags:Due to deficiency of spleen and kidney Turbid dampness stasis, Transforming growth factor β1, Hepatocyte growth factor
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