Three-Dimensional Morphometry And Position Of The Wedge Nucleus Of Human Brainstem

Brainstem has been considered as a restricted area of the neurosurgery operation, because the risk of surgery is high and the complications are more. There are no accurate and quantitative description about the spatial form, spatial location and the adjacent to each other of the nucleus in the brainstem. Three-dimensional shape and position of the three-dimensional reconstruction of the wedge nucleus can provide a way for the further study of the brainstem nuclei, and also to provide reference data for the clinical surgery of the brain surgery. This research is involved in this research field in three-dimensional shape and position of the brainstem nuclei, and to lay the foundation for future accurate quantitative three-dimensional study of brainstem nuclei.First, determine the frame of reference. To facilitate research and clinical application of the principles, to establish suitable for positioning steady state reference coordinate system of the brainstem nuclei.Then, the three-dimensional reconstruction. The image correction processing, the use of automatic segmentation+manual segmentation method of combining image segmentation, the two-dimensional contour image data of the wedge nucleus. Of three-dimensional reconstruction using the marching cubes (of Marching the Cube), three-dimensional shape model.Finally,measurement of three-dimensional data and the shape of the average. Two cases of three-dimensional shape of the wedge nucleus indicators to measure, the signed distance map superimposed on the two wedge nucleus shape average, an average wedge nucleus shape and measure the three-dimensional indicators.Through research, continuous, and clearly show the nuclei of the medulla oblongata map, of all cases of wedge nucleus and average wedge nucleus, surface smooth, natural and realistic three-dimensional shape model, and had various cases of wedge nucleus and the average wedge nucleusthe three-dimensional shape data The data indicate that The wedge nucleus is one pairs were symmetrical and the shape of irregular nucleus, and left nuclei are slightly larger than the right. Nuclei on the left side of the length of9.845mm, the width of5.827mm, height is5.631mm, the volume was137.1mm3and; right side of the length of the nuclei is9.124mm, the width is6.143mm, height is5.355mm, the volume was130.4mm3.