The Pharmacological Action Of Fritillaria Unibracteata Hsiao Et K.C. Hsia

Fritillaria unibracteata Hsiao et K. C. Hsia is plant of F. Liliaceae and widespread naturally in Qinghai-Tibet Plateau. It is known that the extracts have been used in relieving cough, removing the phlegm and relieving asthma. Therefore, it is significant studies for medicine processing. This experiment provided reference for the antioxidative, antimicrobial activities and relieving cough of extracts from Fritillaria unibracteata Hsiao et K. C. Hsia.The main contents and results were as follows :Study on DPPH free radical scavenging activity of methanol extracts and ethanol extracts, filter paper method antimicrobial activity of methanol extracts, ethanol extracts, water extracts, CH2Cl2 extracts and relieving cough of ethanol extracts from the Fritillaria unibracteata Hsiao et K. C. Hsia were examined.1. Study on antioxidative activity of extracts from Fritillaria unibracteata Hsiao et K. C. HsiaThe methanol extracts and ethanol extracts from Fritillaria unibracteata Hsiao et K. C. Hsia showed comparatively common antioxidative activity on test. The methanol extracts of Fritillaria unibracteata Hsiao et K. C. Hsia showed higher activities than those of ethanol extracts. For antioxidation activity, the methanol extracts and ethanol extracts showed DPPH free radical scavenging activity(IC50 543.7 ~ 552.1 ?/μL).2. Study on antimicrobial activity of extracts from Fritillaria unibracteata Hsiao et K. C. HsiaThe methanol extracts and ethanol extracts, water extracts, CH2Cl2 extracts from Fritillaria unibracteata Hsiao et K. C. Hsia showed comparatively strong antimicrobial activity on test. For antimicrobial activity, the methanol extracts and ethanol extracts showed good antimicrobial activity. The 40mg/mL concentrations in the methanol extracts and ethanol extracts was especially good antimicrobial activity(Clear zone on plate 6～12mm). But water extracts and Ch2Cl2 extracts had no effect on antimicrobial activity.3. Study on relieving cough of extracts from Fritillaria unibracteata Hsiao et K. C. HsiaThe ethanol extracts from Fritillaria unibracteata Hsiao et K. C. Hsia showed comparatively good relieving cough on test. The 20, 40mg/kg concentrations in the ethanol extracts was especially good relieving cough. The ethanol extracts of Fritillaria unibracteata Hsiao et K. C. Hsia showed lower relieving cough activities 30.35～31.84% than those of Blank space control.