The Clinical Research On Changes Of The Level Of C-peptide,Insulin And Cortisol In Premature Infants Hypoglycemia

Objective:To investigate the feature of premature hypoglycemia and the factors on hypoglycemia change in premature infant. Methods:Checking the blood glucose and C-peptide,insulin,cortisol concentrations in 150 premature infants in one day,three day and seven day after born. Results:The incidence of the blood glucose disorder was higher in premature infants. There was significant difference between less than 34 week premature infant and greater than 34 week premature infant in the biood glucose disorder (P<0.05). Cortisol was significantly lower in hypoglycemic premature infant than that of control group (P<0.05), and there was significantly higher in hyperglycemic premature infant than that of control group (P<0.05). There were significantly difference between three groups. (P>0.05). And there were not significantly difference between premature infant and that of control group in C-peptide and insulin (P> 0.05). Conclusion:The incidence of hypoglycemia in premature infant is significantly higher. There are some featurs and risk factors of hypoglycemia in premature infant. Cortisol is the risk factor of the hypoglycemia,C-peptide and insulin are not risk factors of the hypoglycemia. It is necessary to preventing hypoglycemia and kickback in checking and intervene..