Urinary Inflammatory Myofibroblastic Tumor Clinicopathological Analysis And Literature Review

Objective:To improve the urinary inflammatory myofibroblastic tumor cognition.Methods:A retrospective 1 case of pseudosarcomatous myofibmblastic prolixfer- ation(PMP)of the urinary bladder and 4 cases of urinary (kidney, ureteral, urethra,the renal hilum)inflammatory myofibroblastic tumor(IMT)patient data and review of the literatures.Case 1,male,38,with"dysuria,hematuria" as the major clinical manifestations, color dopplar ultrasound and CT examination: bladder right side within a tumor size about 2.64 cm×2.56cm,a poor blood supply, scanning enhanced obviously strengthening, consideration for bladder cancer.Case 2, male, 9, with "painless gross hematuria" as the major clinical manifestations, color dopplar ultrasound and CT examination: a tumor in the upper pole of left kidney essence with size about 3.3 cm×3.7 cm, its density is uneven. scanning enhanced uneven strengthening, the blood does not rich, consider left kidney malignant tumors. Case 3, female, 56, with "right flank pain" as the major clinical manifestations, CT: at right next segment ureteral a tumor size 1.4 cm x 2.2 cm, scanning enhanced obviously strengthening, intraoperative saw neoplasm bagging around right ureter. Case 4, female, 41 years old, with " found urethral neoplasm 2 months" for complaints, no other clinical manifestations. Screening see external orifce of urethra has a mass size of 2cm×1cm.Color dopplar ultrasound and IVU and CT material defects. Intraoperative seen since birth papillary urethral mouth outside mass 2cm 2cm x x, about 1cm size. Intraoperative external orifce of urethra a papillary tumor of size about 2cm×2cm×1cm.Case 5,male, 56,with "check-up found left renal cyst, double kidney stones 5 days" for complaints, no other clinical manifestations.Results:Five tumor are complete resection,Case 1:pathological diagnosis for: pseudosarcomatous myofibroblastic proliferation of the urinary bladder.Immunohistoc- hemical: Keratin(+),vimentin (+),desmin(-),actin(-),SMA:a few cells positive, ki-67<3%, CD117(-),CD34(-),S-100(-).Case 2:pathological diagnosis for:left kidney inflammatory myofibroblastic tumor.Immunohistochemical:Keratin(-),desmin(-),actin (-),S-100(-). Case 3:pathological diagnosis for:right ureteral inflammatory pseudotumor (inflammatory myofibroblastic tumor).Immunohistochemical absent.Case 4:pathological diagnosis:urethral inflammatory myofibroblasts cell tumors.Immuno histochemical: vimentin(+),desmin(-).Case 5:pathological diagnosis: the left renal hilum inflammatory myofibroblasts cell tumors.Immunohistochemical: desmin(-),SMA(+/-),ki-67≤1%,CD99(+/-),S-100(-). Five patients follow-up so far,for 0.5~6years,all without recurrence.