The Clinical Epidemiology Study Of Nosocomia Infection Feature In A Three-A Class Hospital

Objective: The study was conducted in a three-A class hospital, to understand the clinical feature of nosocomia infection, including departments, patients, age, as well as the distribution of infection sites and pathogens, and to provide scientific reference for nosocomial infection prevention and control. Methods: the nosocomia infection materials during the period of January 2005 to November 2009 were collected and analyzed retrospectively. Results: 1) A total of 160984 hospitalized patients in five years, which including 4616 nosocomia infection cases, and 4967 infection incidence. Both the infection and infection incidence ratio were 2.87% and 3.09%. 2) The highest nosocomia infection ratio was in the department of ICU, which was 20.99%, followed by the Burn unit (10.88%), Nephrology (8.72%), Hematology (8.55%), Neurosurgery (6.78%) and Neurology (6.02%). 3) The main infection sites were upper respiratory tract (36.34%), lower respiratory tract (31.23%), gastrointestinal (12.97%), and urinary tract (11.38%). 4) of 4967 nosocomia infection patients, 3017 (60.74%) were male, 1950 (39.26%) were female, and the minimum age was 1 day after birth, the maximum was 94 years. The average age was 58 years old. On the other hand, the highest ratio (32.45%) of nosocomial infection is those older than 70 years old. The average number of days in hospital was 30 days. 5) Among 1560 pathogen strains from 4967 cases, 773 strains were G- bacilli (49.55%); 196 strains were G+ (22.41%), 210 were fungi (13.46%); and 259 virus (16.57%). 6) the nosocomia infection pathogens were Gram-negative bacteria, mainly from the lower respiratory tract, urinary tract, surgical incisions, skin and soft tissue, blood. Conclusion: 1) Through the compartment of the infection incidence between different year, different departments, and different infection sites, we aquired the basic data of nosocomia infection trend and distribution, which may provided a strong basis that conduct target detection of nosocomia infection, Develop nosocomial infection prevention and control for hospital key departments and focus groups. 2) The occurance of nosocomia infection is high in ICU, Burn unit, Neonatal ward, Neurology, Neurosurgery, Nephrology and Hematology, which were key departments for the surveillance of nosocomia infection. 3) Infant and old patients were high-risk population of the nosocomia infection, the nosocomia infection sites in Infant patients were respiratory tract and gastrointestinal, which old patients were respiratory tract, gastrointestinal and urinary tract. 4) The timing of hospitalization in nosocomia infection patients were significant longer than that of none-nosocomia infection patients, And the longer duration of hospitalization, the higher nosocomia infection incidence, nosocomia infection aslo extended the duration of hospitalization. 5) the nosocomia infection pathogens were mainly Gram-negative bacilli, Rotavirus is the mostly pathogens in gastrointestinal infection.