Mild Chronic Hepatitis B Chinese Medical Syndromes Distribution Characteristics And With The Analysis Of The Liver Tissue Pathology

Objective:Chronic hepatitis b is our country the main crowd viral hepatitis patients, Chinese medicine diagnosis and treatment of chronic hepatitis b treats is now common methods of hepatitis b. But mild chronic hepatitis b patients with mild, general symptoms what, no disease discernible, this is one of the difficulties in the syndrome differentiation and treatment. And for one to two times of transaminases.associated the mild patients with chronic hepatitis b liver biopsy can better provide basis for antiviral treatment. This study is to investigate the mild chronic hepatitis b (ALT 1-2 x ULN) syndromes distribution characteristics, and analyzes its syndromes and the correlation between the liver tissue pathology.Methods:From August 2009 collection - 2011 February 62 cases were diagnosed as mild chronic hepatitis b patients (ALT 1-2 x ULN) general data and clinical data of detailed records, including history, symptoms, signs, coating on the tongue, pulse condition, laboratory examination (including hbv-dna and hepatitis b full, liver function), and for all patients were done liver biopsy, collect the liver tissue pathology inflammation mobility (G), fibrosis degree (S). Summarizing all material, establish database, the SPSS17.0 medical statistical software, statistical analysis of the data, including frequency distribution method, clustering analysis, etc. Discusses the characteristics of distribution of syndromes, analyze the syndromes regularity and the correlation between the liver tissue pathology.Results:1 To all patients with symptoms, signs, coating on the tongue, pulses, and screened on frequency statistics analysis syndrome appear frequency larger, forming mild chronic hepatitis b major clinical symptoms, signs and tongue of frequency distribution list. Pulse The occurrence of larger symptoms, signs and tongue meridian is liver area unwell, lack of power (mild), NaCha/, food reducing, nausea, dry mouth, to vomit TaiXi, fidgety irritability, inspect content fatigue, reddish tongue or the red tongue, thin yellow or thin white moss, string chakras.2 Use SPSS17.0 statistical software to 62 cases of chronic hepatitis b patients with mild clustering analysis, according to the clustering analysis, combining expert opinions of chronic hepatitis b, for typif ication, TCM syndrome type can be divided into four types:the first class 1 for diseases,28 cases of stagnation; The second kind of pixu (spleen deficient type, for stomach in 25; Category 3 for Yin deficiency, were 6); type Article 4 kinds of 3 cases, for different. In TCM syndrome type and type of pixu stomach diseases stagnation, proportion of main type for 85.48%.3 Explore mild chronic hepatitis b liver TCM syndrome type arom tissue inflammation (G), and fibrosis degree (S) relationship, mild chronic hepatitis b type every syndrome, liver tissue inflammation in the G2 is given priority to, activity of both 83.87%, fibrosis degree to the G1 and G2 primarily.4 Explore mild chronic hepatitis b with laboratory TCM syndrome type, the results show that the relationship index despite mild CHB patients liver function level is not high, but still a more active HBVDNA replication. HBVDNA level and mild chronic hepatitis b TCM syndrome type distribution no significant correlation.5 Explore mild chronic hepatitis b treatment options, for a moderately elevated ALT mild chronic fulminant hepatitis a liver biopsy is very necessary.ConelusionMild chronic hepatitis b 4 kinds of TCM syndrome type of TCM syndrome with chronic hepatitis b type clinical characteristics, basic pathogenesis for chronic hepatitis b, the plague was hot liver toxicity factor, lost by spleen diseases cause stomach stagnation, stomach, long, consumption of pixu injured XieKui blood, appear Yin Yin deficiency, which ultimately leads to viscera function disorder, Yin and Yang, qi unionizing inclusion formed loss situation. Using the method of multivariate statistical analysis syndromes quantitative, make the syndromes to build more standardized, systematic and standard TCM therapy provides certain basis.