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A Clinical Observation Of Therapeutic Effect Of CIK Cells On Malignancies

Posted on:2012-08-01Degree:MasterType:Thesis
Country:ChinaCandidate:J TanFull Text:PDF
GTID:2214330362957213Subject:Cell therapy
Abstract/Summary:PDF Full Text Request
Objective :To observe the short-term clinical efficacy of cytokine-induced killer cells (CIK cells) on malignancies, and the influence on quality of life improvement.Method :Peripheral blood mononuclear cells (PBMCs) were obtained by pheresis. According to the culturing method reported in the literature, CIK cells were induced by culturing the PBMCs with a seires of cytokines. CIK cells were injected back intravenously to the patients after culturing. 23 patients with different types of malignancies were treated with CIK cell therapy from 2006 to 2011. The recent clinical effect and the quality of life improvement of the patients were recorded by following-up visit.Results:In the recent clinical efficacy evaluation, CIK cell therapy were both beneficial to prevention of disease progression and quality of life improvement.Conclusion:CIK cell therapy is eutherapeutic on malignancies.
Keywords/Search Tags:Cytokine-induced killer cells, malignancy, Adoptive immunotherapy, clinical efficacy
PDF Full Text Request
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