Association Between Bone Mineral Density And Coronary Artery Calcification In Aged People

Objective To investigate the association between bone mineral density (BMD) and coronary artery calcification in aged people, explore the risk factors of both BMD and coronary artery calcification, which might contribute to the treatment of both coronary heart disease and osteoporosis in aged people.Methods A total of 45 aged patients admitted in a medical center of Guangzhou during Jun 2007 to Aug 2009 were enrolled. BMD and total coronary artery calcification score (TCS) were reviewed. According to TCS , we divide the patients into TCS normal group(TCS<50)and TCS abnormal group(TCS≥50). BMD of lumbar vertebrate and neck of femur between the two groups were compared, and the correlation between BMD and TCS were analysed. Several available influencing factors of BMD were tested by regression and multiple regression (backward).Results There is significant difference on lumbar BMD between the two groups (P<0.050). L2 BMD correlates with TCS. Sex, high density lipoprotein, body weight and stroke are influencing factors of lumbar vertebrate BMD(P<0.050); High density lipoprotein is influencing factor of BMD of neck of femur(P<0.050).Conclusion There is an association between BMD and coronary calcification, which might be helpful for treatment of both osteoporosis and coronary heart disease.