Clinical Analysis Of 136 Patients With Adenocarinoma Of Lung

BackgroundPrimary bronchus lung cancer, abbreviation lung cancer, is a kind of bronchial mucosa or gland from the malignant tumor, is the one of the most common malignancies in the word, accounting for 16% of all malignant tumor, 28% of all cancer deaths. Its incidence have clear ascendant trend in almost 50 years .In the past 10 years, the risk of lung cancer boost 22% speed in the world every year, 120 million new cases appear each year, about 110 million deaths. In the worldwide, whether male or female, lung cancer have become the main cause of cancer deaths. At present our country lung cancer rates in the city is the first place in malignant tumor, in rural accounted for third place. Since 1996, the cause of death in China has lung cancer tumors in the first draft. About 80 percent of lung cancer is non-small cell lung cancer (non - small, NSCLC) , Non-small cell lung cancer main points by lung squamous cell carcinoma and lung adenocarcinoma, rcomposed mainly by lung squamous cell carcinoma in the past, along with lung cancer in environment factors and social , other factors changes, lung adenocarcinoma have more and more appear in clinical cases, and has its special clinical characteristics, caused our attention. Research purposeAnalysis of lung adenocarcinoma (adenocarcinoma of the clinical characteristics, the company lung staging and influencing factors of pathology.Material and methodTumor hospital of guangzhou medical colleage since February 2009 to December 2010 , 136 patients with disease diagnosed with lung adenocarcinoma, patients for clinical and cases were analyzed retrospectively, based on pathology results . 136 patients with is adenocarcinoma, patients is divided into stage I lung cancer and other staging of lung cancer two groups, with statistical methods, this paper analyzes the age, sex, smoking, clinical symptoms, diagnosis of time on the influence of pathologic stage, in the case,29 lung adenocarcinoma patients who can't surgery use liquid chip technology testing, reach the indiidual therapy and the important reference. Finally discussed with other document.The resultsThis period of our cases of lung cancer 29.3% (136/464), including male 35 patients, women, men and women than 101 cases for the 1:2. 89. Lung adenocarcinoma of radiological findings is not complicated, but not easy distinguish with pneumonia venereal change and other isolated pulmonary nodules lesions, easy cause the misdiagnosis identification. If patients have a cough, sputum chest distress, via regular short anti-inflammatory symptoms .antitubercular treatment is invalid, imaging examination reealed lesions in the lung, round for around or oval lobulated mass, should be highly suspected lung cancer, and especially women without smoking history, lung adenocarcinoma is highly suspected. Other factors in lung adenocarcinoma in no statistical significance, liquid chip technology test for lung adenocarcinoma is important indiidual therapy, gender in stage I lung adenocarcinoma and other staging patients with lung adenocarcinoma proportion are statistically significant differences.conclusionLung adenocarcinoma relationed with smoking unlike other non-small cell lung cancer (non small - cancer cell, NSCLC) , the kind of this lung cancer , women is in common, and doesn't have a smoking history, is a common non-small cell lung cancer; Due to the variation on image, cause delayed treatment by misdiagnosis; Gender in stage I lung adenocarcinoma and other staging patients with lung adenocarcinoma proportion are statistically significant differences, women in patients with stage I lung adenocarcinoma is significantly higher than male proportion. The treatment of lung adenocarcinoma is operation for the Lord; After resection for completeness of lung adenocarcinoma recommend adjuvant chemotherapy. For not surgery patients with lung adenocarcinoma liquid chip technology applicat ERCC1, RRM1, TUBB3mRNA detection expression level, according to the results of the "individual" chemotherapy, can improve chemotherapy curative effect.