The Clinical Research Of Using The Method Of Nourishing Kidney And Invigorating Spleen To Treat Diabetic Nephropathy

Object:Objectively evaluate the method of nourishing kidney and Invigorating spleen to treat Diabetic Nephropathy of spleen and kidney deficiency syndrome of clinical efficacy and safety, preliminary discussion on its mechanism, in order to offer clinical treatment of diabetic nephropathy new remedial approach and reliable basis.Methods: This study included 50 patients who were diagnosed for diabetic nephropathy in phaseⅢ～Ⅳwith spleen and kidney deficiency, they were further divided into two groups randomly. Both groups are treated with regular modern medicine. Besides the normal treatment, the treatment group(25) was added the decoction. Twelve weeks later,the changes of clinical symptom and laboratory index were examined.Result:1.The total effect of the treatment group is 92%, and the contrast group is 32%,there is a significant difference (P<0.001).2.The two groups all can alleviate clinical symptoms; reduce blood glucose, blood lipid,urine protein, CysC, etc. However, the effect of the treatment group is much better than the control group at alleviating clinical symptoms; lowering cholesterol, triglyceride, urine protein, CysC(P<0.05).Conclusion:the method of nourishing kidney and Invigorating spleen can improve clinical symptoms of DN patients in phaseⅢ～Ⅳobviously, correct lipid metabolic disorders,reduce the urinary protein significantly, adjust the function of renal,and finally prevent the progression of DN. It has better efficacy and less adverse reactions than western medical treatment.