A Mate-analysis Of Primary Closure Versus Routine T-tube Drainage In Laparoscopic Choledocholithotomy

Objective:To evaluate randomized controlled trials(RCTs) of clinical research of primary closure versus routine T-tube drainage in laparoscopic choledocholithotomy(LCD) and provide scientific basis by systematic review for clinical research.Methods: Studies on comparison between primary closure and routine T-tube drainage in laparoscopic choledocholithotomy were identified. All the randomized controlled trials were included for Meta analysis with Rev Man 4.2 software.Results: Twelve eligible randomized controlled trials showed 1204 LCD. The result of meta-analysis indicated that it had significant difference in the risk of recent complications and operative time and post-operative staying time in hospital by comparison between primary closure and T-tube drainage(P<0.01,P<0.01,P<0.01).Primary closure decreases the chance of recent complications and shortens both the operative time and the post-operative staying time in hospital greatly. But the risk of long-term complications had no significant difference between both of them(P>0.05). Primary closure won't increase the risk of long-term complications.Conclution: The meta-analysis indicated that primary closure can be recommended for routine and safe application. It can not only shorten the operative time and the post-operative staying time in hospital greatly, but also decrease the risk of recent complications and avoid the potential complications related to the T-tube drainage.