| Objective:To study the significance of central venous pressure(CVP) for assessing the volume status and guiding the ultrofiltration volume in maintenance hemodialysis(MHD) patients.Methods:Indicators before and after single hemodialysis of 36 MHD patients in stable condition had been observed and recorded by a matched pair design with cross-reference. And the indicators involved CVP, ultrofiltration volume, blood pressure(BP), heart rate(HR), the incidences of low blood pressure and muscular twitching, the interdialytic weight gain(IDWG), the morning blood pressure in non-dialysis days, incidence of heart failure, admission rate due to cardio-cerebrovascular diseases, the shifts of cardio-thoracic ratio(CTR) and so on. This procedure had taken 6 month, and the former 3 month as a control group without monitoring CVP and the latter 3 month as an observation group with the CVP supervised. Then all the indicators in the two parts were compared. Results:There were significant differences in incidences of low blood pressure, muscular twitching, interdialytic heart failure and the the morning blood pressure in non-dialysis days (P<0.05), while the CTR and admission rate due to cardio-cerebrovascular diseases did not significantly differ. In a single hemodialysis, the decline of CVP correlated with the rectified ultrofiltration volume (r=0.587). When CVP delined lcm H20, the rectified ultrofiltration volume was 9.89+3.57. It was significantly lower in diabetic nephropathy(DN) patients than in the non-DN patients[(8.26±2.84) vs(11.51±4.08)ml/kg. cmH20, (P<0.05)].Conclusions:Central venous pressure is helpful to the evaluation of volume status in MHD patients, and it has a guiding significance to adjust ultrofiltration volume auurately. |
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