Influence Of Drynaria Fortunei Aqueous-extract On Orthodontic Tooth Movement Of Rats

With the development of society and the raise of people's economy level,people need extensive exchanges and communication, and the demand for beauty increase, including facial appearance as an important part of the urgent requirement of people. Malocclusion influence not only language, digestion, breathing and other functions, but also maxillofacial beauty which has significant impact on their social communication and individual mental and physical growth. Orthodontic tooth movement based on the biological plasticity of jaws can improve both the patient deformity, face type, make its appearance beautiful and chewing, pronunciation as well as other functions. Because of the race evolution and change of dietary structure, the rate of jaws deformities and people demanding orthodontic treatment have increased in recent years. Because the orthodontic treatment is long, how to shorten the treatment, accelerate orthodontic tooth movement, prevent periodontal tissues from excessive damage and avoid the occurrence of side effects have been the pursue orthodontics.Prostaglandin(Prostaglandin, PG),adenosine cyclophosphate(cAMP), vitamin D have been demonstrated to accelerate orthodontic tooth movement. However,the unclear function and their high price for long-term use make it difficult to use in clinic. The traditional Chinese medicine is extensive and profound and there are so many Chinese medicine theory and herbs can be exploited and used in practice and research. Drynaria fortunei which is common in TCM prescriptions for fracture can promote healing of bone fractures and strengthen kidney function. Fracture healing is the process of bone reconstruction, which is the same as alveolar change in orthodontic teeth treatment. According to above theory, our experiment has selected classic traditional Chinese medicine drynaria fortunei with "psoralea corylifolia strong kidney" efficacy.Based on traditional Chinese medical theory and methods as well as modern research methods, we have designed this experiment.Purpose:To investigate the influence of Drynaria Fortunei aqueous-extract on orthodontic tooth movement of rats.Methods:Experimental model for orthodontic tooth movement of rats was used.48 SPF female Wister rats were randomly divided into two groups:experimental group and control group. After applying orthodontic force 7 days,14 days,21 days and 28 days, all rats were killed in batches, with rats'skulls separated. Measure the movement distances of maxillary first tooth and alveolar bone density in root apical site of mandibular molars.Determine serum calcium,phosphorus and zinc levels 7,14,21,28 after orthodontic appliance were fixed.All the results were analyzed by PASW Statistics 18.Results:The distances of tooth movement and the alveolar bone density in the experimental group were both higher than that in the control group. The differences between the two groups were statistically significant(except those indicators measured at 7 days after applying orthodontic force).After orthodontic appliances were fixed,the serum calcium and zinc levels of the two groups both declined and serum phosphorus increased,but the experimental group was more significant.The difference had statistical significance.Conclusions:In orthodontic tooth movement of rats, aqueous-extract of Drynaria Fortunei can relatively increase the alveolar bone density, regulate serum calcium,phosphorus and zinc levels,speed the orthodontic tooth movement of rats.