| Background:Primary bronchial lung cancer is one of most common malignant tumors, among which, non-small-cell lung cancer accounts for 80%.80% of Patients are in the advanced stage (stagelllB or stagelV).It's 5-year survival rate less than 10%. The incidence of lung cancer and mortality rates are rising in the past 20 years.The mortality rate of it has been ranked first and shows the largest increase among all malignant tumors, and a continuous upward trend. It's not obvious of early symptoms, and prone to metastasis. Most patients has been in the advanced stage at the first time of diagnosis, or even the tumor has been transferred. No surgery can be obtained. The only way is the combination of chemotherapy and radiotherapy, but the effect is far from our expectation. The chemo-radiotherapy for patients often brings a series of toxicity, which lead to immune disorders and declination in immune in functions of patients.There are advantages in use of traditional Chinese medicine for reducing side effects of chemotherapy and improvement in life quality and symptoms of patients, the research is about the effect of Compound Astraguls Liquid combined with chemotherapy on advanced lung cancer treatment. Compound Astraguls Liquid is made of four kinds of herbs'extraction of water-Astragalus, Ginseng,Huang Jing,Citrus reticulate Bianco.It's a effective recipe which is examined by clinical use.Objective:To explore the therapeutic effects with toxicity reducing on treating the advanced lung cancer of deficiency of QI and YIN with Compound Astraguls Liquid combined with chemotherapy.Methods:61 cases confirmed primary advanced lung cancer patients were randomly divided into two groups.31 patients of the treated group were treated with Compound Astraguls Liquid and chemotherapy.30 patients in control group were treated with chemotherapy. The treated group:compound astraguls liquid was used about 10ml, three times of day. It applied from a week before chemotherapy to the end of treatment. All of other treatments were the same. The effects of treatment were be observed after two courses of chemotherapy through some stardards. Statistic was analyzed by spss 17.0.Result:The level of peripheral blood leukocytes and hemoglobin in treatment group dropped letter than control group (p<0.05). The incidence of nausea and vomiting was reduced (p<0.05).Other toxicity was statistically significant. The change of T lymphocytes among two groups has significant difference.The immunity function in treatment group is better than the control one.The quality of life in treatment group is better than the other group. The KPS in former group is higher than the latter one (p<0.05).There was no significant difference in relieving TCM symptoms between two groups.However, the differdence of the symptoms on deficiency of QI and YIN is of significance in statistics science (p<0.05).Conclusion:Compound Astraguls Liquid can dissolve the hmatologic toxicity and gastrointestinal toxicity, enhance the recovery of immune function, improve quality of life and relieve symptoms, which is to achieve the purpose of attenuated. |
PDF Full Text Request