The Correlation Analysis Between Different Strauss Classification Of Diabetic Foot And TCM Blood Stasis Syndrome Score

Objective:Discussing the association between different Strauss classification of diabetic foot and TCM blood stasis syndrome score to provide the basis and direction of Integrative Medicine for the treatment of diabetic foot blood circulation.Methods:Selecting 83 patients who are diagnosed with with diabetic foot as the experimental group and 20 patients who are meet the diagnostic criteria for diabetes for the control group. Patients with diabetic foot are divided into near normal wounds (A grade), the problem wounds (B grade) and ineffective wound (C grade) three groups by Strauss criteria of diabetic foot. Also all research objects are divided into without blood stasis, mild blood stasis and severe blood stasis three groups set by the scores of "blood stasis points diagnostic criteria" of Chen keji. Count the number that use case or percentage, using Linear-by-Linear Association. Analysis the association between different Strauss classification of diabetic foot and TCM blood stasis syndrome score. All subjects were measured fasting blood glucose, postprandial 2h plasma glucose, glycosylated hemoglobin, cholesterol TC, triglyceride TG,low density lipoprotein LDL, high density lipoprotein HDL, measurement data using (χ±S) and single factor analysis of variance,comparing the differences among each group divided by Strauss criteria of diabetic foot and blood stasis severity in general, history and biochemical data.Results:Met inclusion criteria 20 cases of control group and 83 patients group, Separately according to diabetes foot Strauss grading and blood stasis degree grouping, In the gender, age, height, body mass index and hypertension course without influence of the comparison results (p>0.05):1.The control group respectively with A, B and C level three groups of postprandial 2h blood sugar more difference (p<0.05); Among A, B and C level,postprandial 2h blood sugar have no obvious difference(p>0.05); The control group, class A HbAlc respectively with the class B and class C more difference (p<0.05); Strauss grading each group fasting plasma glucose were not significantly difference (p>0.05);The control group respectively with A, B and C level three groups TG, TC, LDL and HDL more statistically significant difference (p< 0.05); Among A, B and C level, TG, TC, LDL and HDL have no significant difference (p> 0.05).2. Fasting blood glucose, HbAlc and postprandial 2h blood sugar of severe blood stasis group with non-blood stasis group more difference (p<0.05). HbAlc and postprandial 2h blood sugar of mild stasis group with non-blood stasis group more difference (p<0.05). The TC TG level of non-blood stasis group respectively with mild and severe blood stasis group more significant difference (p<0.05);Among the blood stasis group, LDL have difference (p< 0.05);Among the blood stasis group, HDL have no difference (p< 0.05).3 Diabetes foot Strauss classification rating and blood stasis negatively correlated quantitative score (r=-0.509, p=0.000); Blood stasis degree and diabetes foot Strauss grading exist linear relationship (p< 0.05).Conclusions:1 Patients with diabetic foot have poorer blood glucose control than diabetic patients, also they have lipid metabolism disorders, HbAlc may reflect the severity of diabetes foot strauss grading and blood stasis.2 High blood glucose especially postprandial hyperglycemia and lipid metabolism disorders such as TG,TC,LDL areimportant risk factors of formating and developing blood stasis. LDL can be used as the blood stasis severity reflects objective indexes.3 With diabetes foot Strauss grading the severity of the increase, blood stasis grade quantitatively the corresponding increase, Strauss classification can be used as a treatment for activating blood circulation and eliminating stasis diabetic foot simple quantitative index.