| Object:Design a drainage system that can regulate a constant negative pressure, screen different materials in the drainage tube, monitor the drainage effect, determine the clinical basis of the best drainage, and evaluate effect on the flap survival based on the drainage at constant negative pressure.Methods:First, design and build a constant negative pressure drainage device that can be regulated to ensure the best negative role in the wound, assuming full drainage to promote wound healing. Use the most common clinical PVC pipe, latex tubes and silicone tubes (were negative and recovery of tolerance values for comparison of flexibility) and three types of drainage tube drainage flaps. Observe the contrast for 12,24,36,48 and 72 hours for each phase of the drainage tube drainage in each group to determine the best clinical flap with drainage material. Three groups of flaps were designed concurrently; 1) constant drainage,2) without a constant negative pressure drainage and 3) drainage alone (no negative pressure) drainage flap. In 12,24,36,48 and 72 hour phases, compare the last drainage in each group. After 7 days, use an image analysis method to calculate the survival rate of flaps in each group, statistical analysis methods for the three different drainages and flap survival area of the final phase.Results:1. On three different materials of negative pressure suction drainage tube, drainage tube distal occlusion, PVC pipe wall deformation of the negative value appears-(38±1.85), latex tube wall deformation pressure value occurred-(25.6±1.92), the silicone tube wall deformation negative values appear-(30.5±2.39), Although the negative value is at the maximum tolerance of PVC pipe, at it's worst case reduced diameter, there was varying elastic recovery. In contrast, the silicone tube reduction showed good elastic recovery.2. Comparison of the toughness of the silicone tube and latex tube had the following results. a)silicone tube group afer 12-hour drainage was(4.12±0.56),b)latex tube group afer 12-hour drainage was(2.15±0.76) compared from t12=9.25,P12=0.007；c)silicone tube group after 24-hour drainage was(2.73±0.70),d)latex tube group after 24 hours volume was(1.66±0.56), compared from t24=8.21,P24=0.015；e)silicone tube group after 36-hour drainage was (1.69±0.32)f)latex tube group after 36-hour drainage was (1.28±0.42), compared from t36=7.37,P36=0.011；g)silicone tube group after 48-hour drainage was (1.33±1.14)h)latex tube group after 48-hour drainage was(0.89±0.46), compared from t48=4.14,P48=0.000；i)silicone tube group of 72-hour drainage was (0.76±0.33)j)latex tube group after 72-hour drainage was(0.6l±0.25), compared from t72=3.22,P72=0.000；k)silicone tube group of former drainage extubation was (10.63±1.96)1)latex tube group of the total drainage before extubation was (6.59±1.326)Comparing the total income t=10.97,P total=0.000.PVC pipe group 12 hours to (2.19±0.47),24 drainage hour drainage was(1.07±0.41),36-hour drainage was(1.10±0.41),48-hour drainage was(0.97±0.15),72-hour drainage was(0.45±0.32),before extubation The total drainage volume was (3.78±1.76).latex tube, PVC pipe group reached t12=7.16,t24=6.83,t36=6.37,t48=3.41,t72= 2.25,t total=6.97,P12=0.006,P24=0.013,P36=0.000,P48=0.000,P72= 0.000,P total=0.000,summary,three different drainage tube at the time points of the t values≥2.52,P values<0.05,statistically signiFicant.A fuller description of the silicone tube drainage,stability,stronger.3.Three different comparison drainage device:a).A constant negative pressure drainage device group for 12-hour drainage was(3.25±0.98)；b)Without a constant negative pressure drainage system group for 12-hour drainage was(2.37±0.83),compared from t12=10.78,P12= 0.017;c) A constant negative pressure drainage device group for 24-hour drainage was (2.85±0.90)d) Without a constant negative pressure drainage system group for 24 hours drainage was (1.99±0.86), compared from t24=9.21, P24= 0.016;e) A constant negative pressure drainage device group for 36-hour drainage was (1.93±0.62)f) Without a constant negative pressure drainage system group for 36-hour drainage was (1.30±0.52), compared from t36= 9.97, P36= 0.004;g)A constant negative pressure drainage device group of 48-hour drainage was (1.45±1.04);h) Without a constant negative pressure drainage system group of 48-hour drainage was (0.96±0.66), compared from t48= 5.77, P48= 0.027;i) A constant negative pressure drainage device group of 72-hour drainage was (0.86±0.43);j) Without a constant negative pressure drainage system group of 72-hour drainage was (0.86±0.43), compared from t72=4.19, P72= 0.004;k)A constant negative pressure drainage device group before extubation total drainage volume was (10.42±2.66)1) Without a constant negative pressure drainage system group before extubation total drainage volume was (7.48±2.12), comparing the total income t= 13.65 and P total= 0.003.No negative pressure drainage system group of 12-hour drainage was (1.19±0.47),24 hour drainage was(0.87±0.41),36 hour drainage was (0.32±0.41),48 hour drainage was (0.37±0.15),72 hour drainage was (0.00±0.00), before extubation The total drainage volume was (2.43±1.28). Without a constant negative pressure drainage system and no negative pressure drainage system group reached t12=8.28, t24=7.36, t36=6.88, t48=5.42, t72=4.16, ttotal=11.65, P12=0.014, P24=0.012, P36 = 0.007, P48=0.002, P72=0.000, Ptota,= 0.000, In summary, the negative pressure drainage devices at the three different time phases compared t values≥3.77, P values<0.05, are statistically significant. Shows a constant negative pressure drainage device liquid drainage flap fullest.4. A comparison of three different flap survival rates of negative-pressure drainage devices:a)A constant negative pressure drainage device group flap survival rate was (67.92±3.56)%,b)Without a constant negative pressure drainage system group flap survival rate (60.04±3.55)%,c)No negative pressure drainage system group flap survival rate (53.04±2.59)%,The "constant negative pressure drainage device group of flap survival rates" was significantly higher than that of the "without a constant negative pressure drainage system group". The no negative pressure drainage system group (t=18.21, P<0.01), without a constant negative pressure drainage system group survival rate was higher than no negative pressure drainage system group (t=20.29, P<0.05).Results indicate a constant negative pressure drainage device can be made to promote flap healing and reduce recurrence of skin flap necrosis.Conclusion:1. A constant negative pressure drainage system can be regulated.2. PVC tube,latex tube and silicone tube are commonly used in clinical management. Vacuum suction drainage flaps and elastic recovery properties, were found to be the most suitable for the flap drainage in silicone tube.3. Animal experiments show that the draining effect of self-regulation of a "constant negative pressure drainage device" compares to a "without a constant negative pressure drainage system installation", and no negative pressure drainage system drainage, drainage to the fullest, the best skin flap healing. |
PDF Full Text Request