Measurement And Analysis Of Allergens SIgE And Serum TIgE,ECP Of Asthma

Objective:To investigate the allergens categories of adult with asthma and provide scientific basis for its prevention and treatment.To investigate the diagnostic value of serum total immunoglobin E(TIgE) test in asthma.Methods:Ninty adult with asthma were detected the reactions to 6 kind of inhalation and 12 kind of ingestion of the mixed-allergen-specific IgE(SIgE) and total immunoglobin E(TIgE) using Rapid automated detection system (CAP).Results:In 90 patients with asthma, the majority of mixed inhaled allergens are Wx3 (artemisia, plantago, chenopodium genus, solidago, urtica) and Hx2(house dust, dust mites, flour hiding, cockroaches), the majority of mixed Food allergens are Fx3 (wheat,oats,corn,sesame,buckwheat), Fx5(protein,milk,cod fish,peanuts,soybeans).TIgE positive rate was 62.22%,the majority of patients with asthma were with 1-3 main mixed allergens. Type,ECP levels were correlated with TIgE.Allergen type has no significant correlation with ECP.Serum TIgE in SIgE positive group was significantly higher than SIgE negative group, P<0.01.Compared with SIgE negative group,ECP is no significant difference with SIgE positive group, P>0.05.Conclusion: Wx3(Artemisia,Plantago,Chenopodiumgenus,Solidago,Urtica)is the most important mixed allergens of bronchial asthma in xinjiang.Mixed allergen initial screen the major types of allergens in patients.If screen positive, the individual allergens can be further determined.TIgE can be used to suggest the probability of allergies, and help doctors decide whether a group of Patients need further examination. When the result was negative in common inhalant allergens test. ECP can not judge.allergies in patients.The results may provide the guideline tospecific immunity therapy (desensitization treatment).