Gender Differences In Type 2 Diabetic Microangiopathy

Object:To analyze the Gender differences in diabetic microangiopathy of 1033 patients with type 2 diabetes of Enducriology departmant of the First Affiliated Hospital of Xinjiang Medical University. Methods:1033 patients(male 655, femal,378) with type 2diabetes mellitus(T2DM) were elected from Enducriology departmant of the First Affiliated Hospital of Xinjiang Medical University from January 2009 to January 2010. Their living background were registered including age, the duration of diabetes,family history, smoking, drinking, body mass index, blood pressure as well as indexes about laboratory examination (Fasting glycaemia, postprandial 2 h glycaemia, fasting insulin, postprandial 2 h insulin, Cholesterol(TC), triglyceride(TG), low density lipoprotein(LDL), high density lipoprotein(HDL), glycosylated hemoglobin A1 (HbA1c),24 h urinary albumin x 3 times urine, Urine). Diabetic retinopathy(DR), and diabetic nephropathy (DN) were diagnosed according to international clinical classification fluorescence fundus angiography,and 24-hour urinary albumin. Result:female patients compared with male patients in 1033 patients diagnosed T2DM, showed increase in age, the duration of diabetes, and hypertention (P< 0.05); But showed decreases in hyperlipidemia, smoking and drinking (p<0.05); both female and male patients had a high prevalence of diabetic microangiopathy, the difference was statistically significant (P<0.05), in which the female diabetic retinopathy prevalence were significantly higher than male (P<0.05), but the prevalence of diabetic nephropathy was lower than male (P<0.05). Conclusion: Age, duration of diabetes, obesity, smoking, blood glucose control, hypertension, hyperlipidemia are closely related to the T2DM diabetic microangiopathy. both men and women have a higher prevalence of T2DM diabetic microangiopathy; the female diabetic retinopathy are much higher than male, but the prevalence of diabetic nephropathy is lower than male.