The Clinical Analysis On The Relation Of Type 2 Diabetes Melitus And Coronary Heart Disease

Type 2 diabetes with its rapidly growing prevalence, has become a major public heath problem. It associates with an increased risk of cardiovascular desease.Prior to menopause, Woman are at a much lower risk of coronary disease motality than man are .but it is widely believed that diabetes"erases"this female advantage, increasing the risk of heart diseas much more in woman than in man.Many prospective cohert studies have also proved that this excess risk for cardiovascular desease seems relatively higher for female than for male diabetic patients.What is the reason for this persistent and significant difference between woman and men? Most studies have domonstrated that the difference in cardiovascular risk between the sexes is not accounted for known cardiovascular risk factors (like age, duration of diabetes and systolic blood pressure).At present, several mechanisms could explain why diabetes has a greater adverse affect in women than in men. People found that women with diabetes not only have significantly higher levels of blood pressure and lipids (high low-density lipoprotein cholesterol and high triglycerides) than men with diabetes. This would potentially explain why, after adjustment, the attenuation of the relative risk was considerably greater among women with diabetes than it was among their male equivalents.That suggestes that the sex difference in coronary heart disease risk is mediated in large part by differences in the levels of cardiovascular risk factors. This may be a consequence of diabetes inducing a more adverse cardiovascular risk profile in women, combined with a reduced likelihood of women receiving standard treatment and attaining recommended levels of other coronary heart disease risk factors.In this article, our goal is to investigated sex disparities in control of modifiable cardiovascular disease risk factors among patients with diabetes. The results show that 2-hour postprandial glucose and HbA1c have been higher significantly among women with diabetes, as compared that among men with diabetes, which was statistically significant (P<0.05). HDL cholesterol level are lower in diabetic women than in diabetic men, which was statistically significant (P<0.05). LDL cholesterol level are higher in diabetic women than in diabetic men, which was statistically significant (P<0.05). But fasting plasma glucose and blood pressure are similar between two group patients, which was not statistically significant.We find that in type 2 diabetic patients with cardiovascular desease , poorer control of LDL cholesterol,HDL cholesterol,2-hour postprandial glucose and HbA1c for women may contribute to the sex disparty in cardiovascular desease mortality trends. The excess risk of coronary death associated with diabetes is substantially higher in women than it is in men. More aggressive treatment and better control of other coronary heart disease risk factor levels in women with diabetes is likely to substantially reduce the excess coronary heart disease mortality seen in this subgroup.