| Ganoderma lucidum is China's traditional medicinal Macrofungi with a long application history, there is functions improving sleep quality, resisting the tumor and alleviating fatigue.Modern study indicates that its main active components is polysaccharide and triterpene. However Ganoderma cultivation history is only dozens of years, at present tree cultivation and bag cultivation was two main methods.Because of a wide range of sources of raw materials,the bag cultivation will have a wide application.Salvia Miltiorrhiza Bge.,Chrysanthemum Morifolium Ramat. and Ptatycodon grandi florum A.DC. were all high application volume of traditional Chinese medicine, and the annual drug output reached tens of thousands of tons, Except its medicinal parts, The non-medicinal parts were not more full used.This article made use of three Chinese medicinal materials site of non-medicinal fungus Ganoderma lucidum culture, by Ganoderma lucidum agronomic index and active ingredient content, cost three areas to assess whether as the cultivation of a new type of material for the production of Ganoderma lucidum and select the optimal formula,on the best formula to get Pharmacodynamics evaluation of Ganoderma lucidum fruit body.1. The formula of the optimization of Chinese herbal medicines for Ganoderma cultivation.Salvia, Chrysanthemum and Platycodon grandiflorum 3 Chinese herbal medicines is the formulation of Ganoderma cultivation of raw materials. Each non medicinal parts of Chinese herbal medicine was added by 30%,50%,70%.Experimental determined of Ganoderma lucidum agronomic, the active ingredient content, cost of bacteria three indices, builded a formula optimization of evaluation indexes,and stablished scoring rules,from which we got the best formulas as follows:(1) 30 of Salvia miltiorrhiza non-medicinal part,30.6 of wood,25.4 of cotton seed hulls,10 bran,1 stone paste,3 ssp. (2):50 chrysanthemum non-medicinal part,19.7 of wood,16.3 of cotton seed hulls,10 bran,1 stone paste,3 ssp. (3):50 of Platycodon grandiflorum non-medicinal part,19.7 of wood,16.3 of cotton seed hulls,10 bran,1 stone paste,3 ssp.2. The evaluation study for the Pharmacology of Ganoderma lucidumThis chapter evaluated Ganoderma lucidum fruitbody effect change cultivated with the best formula that respectly were 30% Salvia Miltiorrhiza non-medicinal part group,50% chrysanthemum non-medicinal part group and 50% of Platycodon grandiflorum non-medicinal part group.test Results showed that maximum tolerance dose of mice on Ganoderma lucidum fruitbody was more than 100 g pharmacognostic /kg body weight.50% of medicinal for the parts of the group had a significant role of boosting your body immunity and promoting the sleep; 50% of Platycodon grandiflorum non-medicinal part group had a significant role of promoting the sleep and hibiding to s180 though of mice; 30% Salvia Miltiorrhiza non-medicinal part group have a significant roleof hibiting though s180.Ablove all, in Ganoderma of production, we can use non-medical parts of Salvia Miltiorrhiza, chrysanthemums, Platycodon grandiflorum as the main raw materials to cultivate Ganoderma lucidum. Its active Components contents and medicinal effects have changed compared with control.It can achieve cycle of Medicines and reduce production cost, so it is of significance to production and application of Ganoderma lucidum. |
