Compound Antioxidants And Exercise Training On Free Radical Metabolism And Antioxidant Capacity Of Rat Liver Tissue

64 male wistar mice were randomly divided into four groups: C (Control Group), T (Training Control Group), S ("Compound Antioxidants"Supplementation Group), TS (Training"Compound Antioxidants"Supplementation Group). Together with pure water by a certain ratio, the"compound antioxidants"beverage is made from sea buckthorn, ginseng, Chinese wolfberry, walnut and various vegetables, fruits, and Chinese herbal medicines that have antioxidant effect. Each group was fed with normal animal feed. After a week of feeding, the T and TS groups were both trained for 8 weeks on the animal run stage. After 9 weeks, the four groups were randomly divided into two sub-groups, i.e. the rest group and the trained group. The content of MDA, GSH and the activity of SOD, CAT, GSH-PX and XOD were measured respectively at the rest state and at the time of the fixed training load. All of the data have been processed by SPSS 12.0 software package with T-check for the comparison between groups and p<0.05 is taken as the standard for markedness. Results: at rest state, the content of MDA of the S, T and TS groups is lower than the C group. And the S group is much lower than the C group (p<0.05). The TS group is lower than the T group. The content of GSH and the activity of GSH-PX, CAT and SOD of the S, T and TS groups are all higher than the C group, among which the GSH content of the TS group is more remarkable than the C group (p<0.05), the activity of CAT of the S group is more remarkable than the C group (p<0.01), the activity of SOD of the S group is much higher than the C group (p<0.05), and the activity of SOD of the T and TS groups is more remarkable than the C group (p<0.01). Compared with the C group, the activity of XOD of the other three groups is lower than the C group, but with no significant difference (p>0.05). After fixed training load, the content of MDA of the S, T and TS groups is lower than the C group, the content of GSH of the T group is more remarkable than the C group (p<0.05 ), the content of GSH of the TS group is more remarkable than the C group (p<0.01), the activity of GSH-PX, CAT and SOD of the S, T and TS groups is more remarkable than the C group, among which that of the TS group is more remarkable than that of the T group, but with no significant difference (p>0.05). The activity of XOD of the four groups demonstrates a declining trend. Conclusions:"Compound antioxidants"and training can decrease the content of MDA of the liver tissue of the mice, inhibit rapid peroxidation and can effectively clear the free radical;"Compound antioxidants"and training can promote the activity of SOD, CAT, GSH-PX in the liver tissue and increase the content of GSH. It may help to improve the body's antioxidant capability in different situations; At rest state,"compound antioxidants"can better promote the activity of various antioxidant enzymes, inhibit the activity of XOD and decrease the content of MDA than in the trained state; The changes of the different antioxidant enzymes in different situations are not the same. For some index, the difference is not significant. Further effort is needed to perfect the study.