Gabapentin Preemptive Analgesia For Gynecological Perioperative Analgesia

Purpose:This article aims to view gabapentin preemptive analgesia on elective gynecological surgery postoperative analgesia.Method:Sixty patients are selected for ASAⅠ～Ⅱin Spinal and epidural anesthesia with gynecological surgery.Sixty cases were divided randomly into two group:gabapentin preemptive analgesia group (group A) and the control group (group B) with 30 cases each. Group A taken gabapentin 300mg in preoperative two hours; B group was treated with placebo. The two groups are combined spinal and epidural anesthesia into the operating room, superadded additional 1% Ropivacaine injection by surgery require, no longer administered epidural at two hours before the end of surgery. Postoperative patients received Patient-controlled analgesia (PCA). The visual analogue scale (VAS) at 2,4,8,12,24h after operation, the total consumption of Fentanyl 24h,PCA the number of effective additional,and the side effect in the two group will be recorded. And the satisfactory degree of patients will be recorded at 48 h.Data process with SPSS17.0 package.Content:1.The general condition of patients and postoperative vital signs 24h blood pressure, heart rate, respiration, blood oxygen saturation between the two groups showed no significant difference(P>0.05).2. VAS score:group A of VAS at different time points after surgery were lower than the group B, but only 4 and 8 hours were significantly (P<0.05).3.The number of button pressed and Fentanyl dosage at 48h in group A were less than that of B(P<0.05).4.Group A of dizziness occurred less,nausea, vomiting, itching and other side effects were lower than the group B,only nausea and vomiting were significantly.Conclusion:Gabapentin used in preemptive analgesia Spinal and epidural anesthesia in gynecological surgery can reduce postoperative pain, decreased postoperative opioid dosage and reduce side effects related to.