Neoadjuvant Radiation Therapy For Carcinoma Of The Cervix ¢ò

Objective:To summarized retrospectively the 3,5-year survival rates of stageâ…¡cervical carcinoma treated by new-adjuvant radiotherapy plus radical surgery. and Neo-adjuvant radiotherapy on the impact of surgery and radiation side effects. and determine the value of neo-adjuvant radiotherapy in the treatment of stage II cervical cancer.Methods:Select eighty four patients with stageâ…¡cervical cancer treated in the Second Hospital of Shanxi Medical University from 2003 to 2007. Thirty four cases received the radio therapy (external radiation and brachytherapy) before the operation. After a rest of ten to fourteen days, radical hysterectomy and pelvic lymph adenectomy was performed. The other 50cases treated radical radio therapy. In Neo-adjuvant radiotherapy group,60Co was used for external radiation, in which the point A dose was 32 Gy, at the same time 192Ir high-dose-rate afterloading unit was used in brachytherapy, with a dose of 20 Gy at pointA. Radical radiotherapy group using the same equipment,After the point A dose reach 32 Gy two pairs change four pairs and add Point B dose of 20Gy, reached a total of 52Gy. At the same time accepted brachytherapy with a dose of 40 Gy at point AResults:â‘ 3,5-year survival rate of Neo-adjuvant radiotherapy group and Radical radiotherapy group:stageâ…¡patients, respectively (90.05% and 85.30%, P< 0.05), (88.56% and 82.90% P<0.05) differences were statistically significant. Stageâ…¡b patients, respectively (88.00%, and 87.10%, P>0.05), (82.03% and 80.90% P>0.05) There was no significant difference.â‘¡Neo-adjuvant radiotherapy on the impact of surgery:Neo-adjuvant radiotherapy, the tumor remission rate was 96.4% (81/84),thirty four patients all received neo-adjuvant radiotherapy can successfully underwent radical surgery, does not increase postoperative complications.â‘¢Radiation side effects:the incidence of the chief radiotherapy side effects in neo-adjuvant radiotherapy group are less than radical radiotherapy group (P<0.05).the differences of two groups have statistically significant.Conclusion:â‘ Neo-adjuvant radiotherapy plus radical surgery in stageâ…¡cervical cancer compared with radical radiotherapy can significantly reduce radiation side effects, without increasing the surgical difficulties and complications.â‘¡Neo-adjuvant radiotherapy plus radical surgery compared with radical radiotherapy can improve 3-year and 5-year survival for stageâ…¡patients', but have differences of insignificance for stageâ…¡b patients...