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Type 2 Diabetic Retinopathy Tcm Syndrome

Posted on:2011-04-27Degree:MasterType:Thesis
Country:ChinaCandidate:Y X ZhangFull Text:PDF
GTID:2204360305472427Subject:Chinese medical science
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PurposeIn this study, carried out in Type 2 Diabetic Retinopathy Clinical Research syndrome.TCM focuses on distribution and evolution of characteristics and syndromes and related laboratory parameters, microscopic fundus changes related to type 2 diabetic retinopathy clinical syndrome differentiation and treatment of standardized reference.MethodIn this study, the Beijing University of Chinese Medicine, Dongzhimen Hospital, Department of Endocrinology diagnosed type 2 diabetic retinopathy patients were investigated, collecting 104 cases of DR patients in general, Chinese medical information and related specialist examination results, laboratory results.Input data and the data were stratified statistical analysis group.Descriptive analysis of statistical methods (Measurement data were rank and non-parametric test, count data were analyzed by X2 test), and check against the distribution of characteristics of candidates analyzed and summarized, using Spearman correlation analysis of the various laboratory parameters, changes in retinal micro-and the relevance of TCM research and analysis.Result1 Study found 104 cases of DR and DR sub-age of the patient type, sub-period, no statistical correlation between age and DR can not be considered linear correlation between stages.The duration of diabetes and DR type and stage was significant, showed a positive linear correlation.Body mass index BMI in the DR type, no distribution between sub-period, but found by the correlation test, BMI is positively linear with DR stages associated with sex.2 Study found that four kinds of diabetic complications in diabetic nephropathy in DR different type, sub-period there were differences in distribution of the remaining three common complications of diabetes (diabetic foot, diabetic arteriosclerosis obliterans, diabetes, peripheral neuropathy) in the DR type between no significant difference in the distribution.3 DR 104 cases of fat are common symptoms in patients with yang deficiency, Qi deficiency, Yin deficiency, blood stasis, Qi Yu cards, phlegm the performance of the different type without a significant difference.Syndromes of phlegm the first place the distribution to account for 93.27%, followed by blood stasis, accounting for 84.62%, yin deficiency, accounting for 78.85%, Qi Yu cards, accounting for 71.15%, dampness, accounting for 67.31%, qi deficiency,64.42%, the frequency of greater than 50%.Distribution of syndrome and symptom scores were statistically tested in the DR no difference between different sub-types.4 Study found 104 cases of patients with syndrome of DR are false is mixed portfolio, and more evidence for the eight combinations, accounting for 24.0%, six card portfolio, accounting for 20.2%,7 card portfolio, accounting for 18.3%, reflecting the inclusion of diabetic retinopathy actual situation, the virtual The basic standard real syndrome.5 The Spearman correlation test and found that glycosylated hemoglobin and phlegm, dampness integration has a positive linear correlation with urinary albumin and yang deficiency, phlegm showed a positive linear correlation with symptoms of retinal hemorrhage, hard exudates, softexudative and Yang Deficiency are linear correlation.6 Renal function (serum creatinine, blood urea nitrogen, GFR) and showed linear correlation with DR stages, according to the correlation coefficient shows serum creatinine and blood urea nitrogen increased with DR stages rise, GFR increased and reduced with DR stages.7 Serum creatinine, blood urea nitrogen and hard exudates, soft exudates showed a positive linear correlation with the extent, GFR and hard exudates, soft exudates showed a negative linear relationship between degree of urinary albumin and soft exudates were positively the linear correlation.Conclusion1 DR condition has little to do with age, but not with DM duration of disease was closely related.2 Diabetic nephropathy, hypertension, hyperuricemia is closely related with the occurrence and development of DR, has important tips significance.3 MuIti-card combination, the actual situation is a mixture of DR significantly syndrome.DR deficiency is common in patients with type-designate Yang, Qi, Yin, standard empirical climate type stasis, Qi Yu.Evolution deficiency syndrome found Yin deficiencyâ†'Qi and Yin deficiencyâ†'Yin and yang deficiency, Yin deficiency diseases through always, Qi and Yin deficiency, Yin and Yang deficiency, phlegm and blood stasis resistance and the development of this disease is closely related.4 Glycated hemoglobin levels and DR phlegm, dampness degree of positive contact with the DR urinary albumin levels in patients with yang deficiency, the degree of positive contact with phlegm.Bleeding, hard penetration, soft permeability changes in retinal micro-level performance and Yang Deficiency positively correlated.5 Renal function (serum creatinine, glomerular filtration rate, urinary albumin) levels and DR severity and changes in retinal micro-close, suggesting that renal dysfunction is associated with DR progression.The Institute selected patients with more limited disease stages, remains to be selected for the sample size for future expansion, hierarchical large-scale epidemiological studies, may have the disease syndrome in a comprehensive grasp of the characteristics and the different card .The clinical significance of climate have a deeper understanding.
Keywords/Search Tags:Type, Diabetic retinopathy, Diabetes, Fundus changes, TCM
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