Effect Of Geese After Nasal Endoscopic Sinus Surgery Nasal Lavage Fluid Of Clinical Observation And Experimental Study On Irrigation

Objective To investigate the influence of irrigating solution of xin'e lavaging solution,given after operation on the therapeutic effect of ESS for chronic sinusitis and investigate the pharmacodynamic effort of xin'e lavaging solution.Methods xin'e lavaging solution was used to irrigate the operated sinus cavity lasted for weeks among 20 cases with chronic sinusitis(type)treated by ESS and 0.9%N.S.was used to irrigate the operated sinus cavity treated by ESS in the same way among 20 cases with control and The blank group not used to any lavaging.Regular nasal endoscopy, Observed in patients with cavity cleaning time and Epithelium of the situation. According Functional endoscopic sinus cavity mucosa after surgery division of the vesting period and deal with the principle of XU Geng to evaluate the effect. Respectively, at postoperative 3 months, 6 months take the Ethmoid mouth mucosa and Observed by transmission electron microscopy.Observate xin'e lavaging on mouse carrageenan paw swelling and Cotton ball granuloma of mice, Investigate the anti-inflammatory effect of xin'e lavaging solution.Result Treatment group and the epithelial cavity clean of the situation are better than the control group and blank groupAnd there is a significant statistical difference( P<0.05 ).TEM observation after 3 months, Treatment group cavity mucosa restore the structure and function better than the control group and blank group And there is a significant statistical difference( P<0.05 ). TEM observation after 3 months, cavity mucosa three groups compared to the situation, Although the treatment group than the control group and blank group, but no significant statistical significance(p>0.05). xin'e lavage fluid of mice paw swelling and granuloma hyperplasia model significantly inhibitedConclusion lavage Nasal with xin'e lavaging solution can more effective in promoting Cavity cleaning and Accelerated epithelium of cavity, effectively eliminate the nasal mucosa edema, promote local blood circulation, Mucosal regeneration and functional recovery. Cavity mucosa restore at least 6 months to complete mucosal epithelialization.Xin'e lavaging solution has a good anti-inflammatory effects.The results for the clinical application provides a pharmacological basis...