Renal Anemia In Rat Serum. The Kidney Shengxue Granules Promote Erythropoiesis Influence Of The Hormone Epo And Anti-fibrosis

purpose: To approach the invigorate kidney–hematosis granula the antifibered to the big rat of the chronic renal failure with anemia(RA) ,the improving effect of RA and the contents of sangui-erythropoietin(EPO). Method: Adopt the adenine to RA model of big rat of,is divided randomly into a model control group ,Chinese herbal medicine treatment group (invigorate kidney–hematosis granula),western medicine treatment group (EPO),the group that Chinese herbal medicine associate with western medicine treatment(invigorate kidney–hematosis granula with EPO).Measure the blood RBC,Hct,Hb,kidney function , transforming growth factor-β1 (TGF-β1) and blood EPO content. Result: the invigorate kidney–hematosis granula treatment RA result and EPO to have no obvious difference(p>0.05), slightly inferior to unite an applied set in Chinese-western medicine treatment(p<0.05), and can degrade the content of the blood BUN,Cr obviously, relieve the nephridial tissue pathological lesion, raise the blood serum EPO and down the blood serum TGF-β1 level (p<0.05) . Conclusion: the invigorate kidney–hematosis granula can cure a kidney anemic effectively and to improve the kidney function obviously, raise the blood EPO content, also have already strengthenned the function that the ability of organism anti-fibered.