The Only Of Blindly Effective Parts Of The Screening And Its Preparations

Lamioplomis rotata (Benth) Kudo, a plant of lamioplomis genus (labiatae family),widely grows in alpine meadow and flood land at altitude 4000m. It distributes in Tibet, Mongolia and Naxi people to promote blood circulation, remove blood stasis, subdue swelling and alleviate pain.That main compounds in Lamiophlomis rotata (Benth) Kudo were reported as flabonoids, iridoids and phenethanol glycoside, but the active components reflecting clinical effectiveness were still unkown. 70% ethanol extraction of the herb, collected in Shiqu county of Sichuan province, was partitioned into four fractions as petroleum spirit, acetic ether, n-butanol and water portion. Guide with initial pharmacological activities test on mice streching model and broken tail model, n-butanol fraction was showed to have obvious analgesic action on reducing the times of mice writing reaction caused by acetic acid and reducing the times of bloodsheding. The portion of water, 30% and 90% ethanolic elution obtained after purification with macroporous resin from n-butanol fraction. 30% of them was found to show strong stanching blood and analgesia activity.Effective in the study were based on the preparation to be effective parts of the mainly Duyiwei intermediates. To improve the preparation Duyiwei bioavailability, and reduce use of volume, We intermediates for the preparation of study materials Duyiwei pills, and to establish the quality standards.