Pharmaceutical Study Of Jiawei Huoxiang Zhengqi Pill

Drop pills belong to immediate effect preparation.It has been application on cardiovascular disease,Disease of respiratory system,infectious diseases For the past few years,With the development of new technology,new adjuvant and improvement of tragacanth facilitie step by step.Traditional Chinese medicine drop pills was be lucubrated,Some of production has been gain favourable social effects and economic returns.Drop pills has become hot spot and focal point of pharmaceutical factory.Take Jiawei huoxiangzhengqi drop pill as model medicine,Under the guidance of traditional Chinese medicine theory and the modern technique,the basic pharmaceutical research of Jiawei huoxiang zhengqi drop pill was achieved together with the selection of manufacturing techniques,establishment of quality standards,the appraise of preliminary stability.To discuss nodus of galenic pharmacy of drop pills which were made of TCM compound recipe through the research and quality evaluation of Jaw huoxiang zhegqi drop pill.On the basis of the function and treatment as well as the characers of the effective component of the herbs,the preparation process is designed to studying the extraction of volatile oil,alcohol-extract and water-extract,the optimum extract conditions about alcohol-extract and water-extract were selected by using orthogonal design which use quite a few assessing norms to evaluate them comprehensively.At the same time With the granule roundness and solution time of the pills,appearing as appraisal index select The ground plasm and the condensing agent.The results are that PEG4000: PEG6000=1:2.5 appear as ground plasm,liquid paraffin appear as condensing agent, the proportion between powder of drug and ground plasm is 1:1.2～1.3.With roundness and weight variation of the pills appearing as by orthogonal test. The conditions:dropill temperature is 80℃,dropill distance is 5cm,dropill velocity is 20 drop/min.We identify Guanghexiang chenp zisuye gancao and baishu with thin layer chromatographic method.Their repeatability is good,and specificity high.With Magnolol and Honokiol appearing as object and index deter-minate content by HPLC,the dissolution experiment was carried out.The preliminary stability test indicates that the packed granule was stable in 3 months.Studies have shown: preparation craft was feasibled,quality standards can be controlled.It provided a valuable reference for the research of drop pills which were made of TCM compound recipe. Research of Traditional Chinese medicine drop pills,Under the guidance of traditional Chinese medicine theory,Oh the basis of the indication and characteristic of drop pill,Choose those anagraph that curative effect is good,compounding simplify,application widespread and have pharmaco-research or clinical report.Make use of new techoloy and new adjuvant,carry out new drug research.Request "security,utility,stabilization,control".