Comparative Study Of Acetaminophen And Throat An Orthodontic Tooth Movement In Rats

abjective To compare the effects that acetaminophen and Chinese herbal medicine have on orthodontics teeth movement and to examine the differences of bone resorption in the pressure area and the expression of COX-2 around the root of the teeth. Methods Forty-eight adult male Wistar rats were divided into three groups of fifteen each: Acetaminophen group,Chinese herbal medicine group and control group. The appliances were placed between molars and incisors. The rats were killed on 1 d, 3 d, 7 d, 10 d and 14 d respectively. Histological examinations were performed on all above samples. Results Analysis of variance showed significant differences between the control group and group given acetaminophen on 1 d,3 d,10 d,14 d.The group given Chinese herbal medicine have the same statistically significant differences on 1 d and 10 d. Conclusions The results indicate that under 40 grams oral administration Chinese herbal medicine or acetaminophen for three days, they affected bone resorption in the short period ,but did not affect bone resorption in the long term, and it might be the analgesic of choice for treating pain associated with orthodontic treatment. Abjective To compare the effects that acetaminophen and Chinese herbal medicine have on orthodontics teeth movement. Methods Forty-eight adult male Wistar rats were randomly divided into three groups of fifteen each: Acetaminophen group, Chinese herbal medicine group and control group. The appliances were placed between molars and incisors. The rats were killed after 1, 3, 7, 10and 14 days respectively. A special tray will be used to take models.The distance of tooth movement were measured and compared. Results Analysis of variance showed significant differences between the control group and the group given acetaminophen on 1 d,3d and 7 d.The Chinese herbal medicine just like the acetaminophen group have statistically significant differences on 3 d. Conclusions The results indicate that under forty grams the Chinese herbal medicine just like acetaminophen did not affect orthodontic tooth movement in the long term, and it might be the analgesic of choice for treating pain associated with orthodontic treatment.