Cai A Mixture Of Addition And Subtraction Treatment Of Her-2 Positive Breast Cancer, The Efficacy Of Clinical Research

Breast cancer is ductal breast epithelial cells in the role of various internal andexternal factors,the cells lose their normal characteristics of dysplasia,which exceeded the limits of self-healing and cancerous diseases.Breast cancer is named "Ruyan"in TCM,is one of the most common cancer in woman,every year about 13 million people were diagnosed with breast cancer, in many cities,the incidence of breast cancer to become the first women's cancer.At present,the comprehensive treatment of breast cancer treatment has become the main method of Chinese medicine in breast cancer treatment in the role and advantages,increasing domestic and international sector of the importance of tumor.The plan will have in medicine and surgery, radiotherapy and chemotherapy,hormonal therapy,biological therapy combined,in patients with physical improvements,reduce the toxicity of radiotherapy and chemotherapy,improving the quality of life,control of tumor recurrence and prolong survival in a significant effect.The complexone of Radix Bupleuri and Tortoiseshell is s basised on the powder of Bupleurum shugan and three Tortoiseshell,and in accordance with the certificate of addition and subtraction,the powder of Bupleurum shugan from the "King Yue quan shu" is basised on the Sini shan from the shahan lun,and added Dried Tangerine peel,oncogenic promoterLovage Rhizome and Szechwan Lovage Rhizome。The effective prescription have curative effect of disperse the depressed liver-energy,administ qi,harmony blood,the indication is depression of liver-Ql.stagnation of liver-QI,the powder of three Tortoiseshell from the book "Wenyi theory."writed by Wu youke who was well-known physician in the late Ming.The prescription is composed of turtle shell,Tortoise Shell,Pangolin Scale,Eupolyphaga seu Steleophaga,Oyster Shell,Stiff Silkorm,White peony Alba,Chinese Angelica and Radix Glycyrrhizae.component, which has efficacy of tonification,may expel female evil and nounish blood and essence;which may expert collaterals,search pathogen,removing stasis by added Pangolin Scale,Eupolyphaga seu Steleophaga,Oyster Shell,StiffSilkorm and to to educate blood and qi by added White peony Alba,Chinese Angelica and Radix Glycyrrhizae.Breast cancer dialectical type,although currently not unified understanding,but Liver depression,breast cancer and blood stasis,development and prognosis of a close relationship.The complexone of Radix Bupleuri and Tortoiseshell may disperse the depressed liver-energy and disperse the depressed liver-energy,for the legislative basis,plus or minus accompany syndrome for many years,is effective.PurposeThe purpose of this study of The complexone of Radix Bupleuri and Tortoiseshell treating HER-2 positive breast cancer patients after the comprehensive effect,for clinical treatment of breast cancer in Chinese medicine to provide effective methods and theory.MethodSelect out-patient treatment in Chinese medicine hospital in Hubei Province of a total of 60 cases of breast cancer patients,all patients have been diagnosed as pathological biopsy invasive ductal carcinoma(infitrating ductal carcinoma,IDC),and in strict accordance with the standards included in select cases.According to clinical treatment in patients with order and the compliance of taking Chinese medicines,were included in the treatment and control groups,all 30 cases,two patients in the treatment of the former age,disease,stage,tumor size,lymph node involvement, estrogen and progesterone receptor situation In no significant difference(P＞0.05),are comparable. The complexone of Radix Bupleuri and Tortoiseshell treatment group to which a mixture of addition and subtraction(mainly Chinese crude drug Snakegourd Fruit 15g,Turmeric Root Tuber 15g,finger citron 15g,Bupleurum chinense 10g,Baical Skullcap Root 10g,dandelion 20g, Chinese sage 15g,cat-scratch grass 15g,Barbated Skullcup Herb 15g,Dried Tangerine peel 15 g,Pinellia tuber 10g,Pangolin Scale 10g,licorice 6g),with the syndrome plus or minus, deficiency of vital energy added dangshen,Milkvetch Root,yin asthenia added Cochinchinese Asparagus Root,Dendrobium,blood deficiency added prepared rhizome of rehmannia, donkey-hide glue,Sanchi,blood stasis added Common Burreed Tuber,Zedoray Rhizome, Cowherb Seed;pyretic toxicity added bistortae,rhizoma,Bungarus minimus,humid heat added Coix Seed white-Kou,constipation added Hemp Seed,rhubarb,upper limbs swollen added plantain herb,tuckahoe,Mulberry Twig,Peach Seed,safflower,Motherwort Herb,Luffa charged,Luffa charged,loss of appetite add carbon Hawthorn,stir-baked FRUCTUS HORDE1 GERMINATUS,Water to cook twice onthe afternoon temperature clothes and a daily control group to Xiao-Ping(manufacturing enterprises:Xi'an Chia Tai Pharmaceutical Co.,Ltd.;approval of the text:State Yao Zhunzi Z61020111;major components:alumbre,Dried Lacquer,Nux Vomica powder,faeces trogopterorum,Hairyvein Agrimonia Herd,Agrimony,niter,Turmeric Root Tuber,Fructus Aurantii.)Treatment,oral,four piece one time,piece three times a day above two groups were treated for two years(the period where there may be intermittent,each The withdrawal is not more than three days,a total of not more than one month),the two groups were observed mainly in patients with medication after the comprehensive clinical efficacy, including the related symptoms and signs,the quality of life,blood,liver and kidney function, tumor markers and recurrent transfers.ResultsComprehensive treatment of the clinical efficacy higher.The treatment group in the main symptoms and signs to improve efficiency for 70.4 percent,30.1 percent for the control group; treatment group in improving the quality of life for 76.7 percent efficiency,control group was 33.3 percent in the stability of tumor markers CEA in an efficient and CA153,respectively 70%in group A and 36.7 percent for group 2 year recurrence rate was 20.0%,60.0%for the control group; statistical,P＜0.05,with statistical significance,and the monitoring of blood,liver and kidney function is not Apparent side effects.ConclusionThis study of Chinese medicine from the dialectical theory of traditional Chinese medicine, clinical breast cancer after operation ofen occurrence stagnation of liver-QI,blood stasis,sputum coagulate,and the deficiency ofqi and blood,deficiency of both vital energy and yin and so on,so found methed of disperse the depressed liver-energy,eliminating stagnation,removing blood stasis,neutralize poison,and tonifying QI,educate blood,taste female,invigorate the spleen.The complexone of Radix Bupleuri and Tortoiseshell treating breast cancer,according to The complexone of Radix Bupleuri and Tortoiseshell treating HER-2 positive breast cancer have a effect in improving the major symptoms and signs And improving the quality of life,stability, liver and kidney function and cancer markers in both films is better than Xiao-ping,the results also showed that could reduce recurrence.The course of the study does not appear obvious side effects,its effect was based on The complexone of Radix Bupleuri and Tortoiseshell of diesel-treating breast cancer Differential Treatment in line with the principles of Chinese medicine, this research note The complexone of Radix Bupleuri and Tortoiseshell of HER-2 positive breast cancer with anti-tumor effect,clinical effective,Worthy of further research and extension.