| ObjectiveChinese coronary heart disease (CHD) patients with TCM and coronary stenosis, a fewlesions, Gensini score, lesions, blood theology changes,lipid change and therelationship between the degree of coronary artery disease (including stenosis, lesioncount) and blood theology changes in lipid change the relationship between theobjective differentiation for the macroeconomic indicators, Discussion analysis fromPhlegm Syndrome diagnosed by coronary angiography in patients with coronary heartdisease and TCM-related.Materials and Methods1. CHD TCM Syndrome reference standard type. Including phlegm syndrome, bloodstasis and Phlegm-compatible cards, gas stagnation, the tools to permit the Qi,Yang-deficiency, Yin deficiency, Shenyang from cards, and on this basis in patientswith coronary heart disease will be further divided into four cards: phlegm syndrome,blood stasis and Phlegm-compatible card PP-Stasis Syndrome (including air stagnation,tools to, Qi and Yang deficiency, Yin and Yang from.)2. 368 cases of CHD patients TCM and CAG-examination, Comparative analysis ofTCM and coronary stenosis, a few lesions, Gensini score, lesions relations.3. 368 cases of CHD patients blood theology, lipids laboratory examination,Comparative analysis TCM type and severity of coronary artery disease, the lesionsand blood theology changes changes in lipids between February 2 relations.4. SPSS 12.0 statistical software used for statistical analysis, measurement data to mean±standard deviation ((?)±s); data between the single-factor analysis of variance.Results1. 368 cases of CHD of the TCM-based distribution: Phlegm compatible card 116(31%) "blood stasis in 74 cases (19%)," phlegm syndrome in 54 cases (15%), "Qi stagnation 30 cases (8%) "deficiency of 28 cases (8%), Yang-Deficiency 28 cases (8%),syndrome in 28 cases (8%) "tools to permit 6 cases (2%)" certification from Yang 4(1%). PP-Stasis Syndrome, Phlegm compatible card no significant difference with theblood stasis. Mainly compared with a statistical significance (p＜0.05). Qi stagnation,the Qi, Yang-Deficiency Syndrome, the syndrome in groups no significant differences,but with tools to permit Yang delinking compared with a significant difference(p＜0.05). Phlegm compatible card, blood stasis, phlegm syndrome and the blockage ofnon-sputum-card between the card there was a significant difference (p＜0.05),especially with the tools to permit Yang delinking compared with more obviousdifferences (p＜0.01).2. Lesion Scope: 368 cases of coronary angiography single vessel coronary arterydisease in 119 (32.34%), Two-vessel disease in 103 cases (27.99%), multi-vesseldisease, 146 cases (39.67%).Coronary artery stenosis: a narrow 157 mildly, moderatelynarrow 258-severe stenosis 247.88 blocked artery total of 755. the total count ofcoronary 67.93% (750/1104). Gensini coronary scoring system was used integral 27.39±11.74, with a maximum of 96 hours, four hours minimum.3. And the extent of coronary stenosis TCM-the relationship between:3.1 The different degree of stenosis in a few cases the TCM-based distribution of theanalysis: mild stenosis in the main gas stagnation (22/368), and tools to permit, nocertificate from Yang; Phlegm moderate compared to the narrow-Card (21/368),phlegm syndrome (21/368). Qi Deficiency Syndrome (16/368), which stagnation andgas, tools to permit Yang delinking compared with a significant difference (p＜0.05);Severe stenosis to Phlegm compatible card (51/368). blood stasis (33/368), phlegmsyndrome (20/368), which Syndromes and other more significant difference (p＜0.05);Phlegm narrow to fully compatible card (26/368), blood stasis (10/368), whichSyndromes and other more significant difference (p＜0.05). 3.2 Degree of stenosis different branches in the TCM-based distribution of the analysis:mild stenosis gas to stagnation (36/755), Phlegm compatible card (33/755). blood stasis(30/755), mainly phlegm syndrome (24/755); Phlegm moderate compared to thenarrow-Card (57/755), phlegm syndrome (51/755). blood stasis (42/755), which yin(30/755), the Yang-Deficiency Syndrome (24/755). Qi Deficiency Syndrome (22/755)have increased; Severe stenosis, a constriction of Phlegm compatible card (123/755,41/755), blood stasis (60/755,20/755), which and non-sputum-Stasis Syndrome moresignificant difference (p＜0.05). Can be seen from: coronary artery stenoses with lesserstagnation gas (73.3%), which Coronary lesions were heavier to Phlegm compatiblecard (66.4%), blood stasis (58.1%), which Taken with the gas lag compared with asignificant difference (p＜0.05). With increasing degree of stenosis, Phlegm compatiblecard, blood stasis, phlegm syndrome, the yin and yang deficiency card number,Stagnation and gas reduction (p＜0.05). Due to Cold permit, the park permit from thesample may be due to a small number, no statistically significant difference in themeaning.4. Coronary lesions and TCM-the relationship between:4.1 Single-vessel coronary artery disease were to air stagnation, the main blood stasis.multivessel disease compared to Phlegm and certification, phlegm syndrome, bleedingcards, yin and yang deficiency evidence-based. Multi-vessel disease in the group phasePhlegm and certification significantly more than phlegm syndrome, blood stasis andYin deficiency (p＜0.05). In a single vessel disease, the park from cards, certificatestools to significantly less than with stagnation, blood stasis, phlegm syndrome (p＜0.05).In two lesions, Phlegm compatible cards, phlegm syndrome, bleeding certification andYin deficiency, Insufficiency of evidence was no significant difference (p＞0.05).4.2 The TCM group, gross coronary artery disease by Yang from several of the tools topermit certification of the Qi stagnation of the gas card to the pulse of Yin deficiency of phlegm syndrome of blood stasis to Phlegm is growing and certification, Phlegmcompatible card, blood stasis, phlegm syndrome coronary artery disease distribution,gross and number of non-smear of blood stasis between the non-significant difference(p＜0.05).4.3 Average by a few narrow tools to support certification of the Qi stagnation of gas toYang Yang or from card to card to the phlegm syndrome of blood stasis to Phlegmcompatible card to the syndrome in turn increased, but a card-no significant difference(p＞0.05).5. Phlegm Syndrome and the number of coronary lesions and Gensini coronary scoringsystem was used calculus: With non-sputum-Stasis Syndrome, phlegm syndrome.Stasis has Phlegm is evidence of coronary Gensini coronary scoring system was usedand scores gradually increased, while blood stasis compatible card blood stasis and non-smear of blood stasis between non-significant difference (p＜0.05) But blood stasisand phlegm syndrome, there was no difference between the (p＞0.05). Phlegmsyndrome and non-sputum-Stasis Syndrome, there was no difference between theobserved cases may be related to several much difference to some extent.6. Coronary lesions with TCM relationships: the TCM-coronary lesions with LADdisease closely related, single vessel disease LAD most (20.7%) and the existence ofcoronary lesions LAD disease is the most (80.7%) of 33 cases LM disease. But simplyLM lesion seen with many other disease; LCX and RC disease in the Chinese-carddistribution was no significant difference (p＞0.05). With the lesions increased Phlegmcompatible card, blood stasis, phlegm syndrome, the syndrome in a gradual increase ingas and stagnation. The symptom reduction (p＜0.05). Due to Cold permit, the parkpermit from the sample may be due to a small number, no statistically significantdifference in the meaning. Anterior descending and circumflex branch of the leftcoronary artery is, the left coronary lesions main evidence is Phlegm-compatible card, blood stasis, phlegm syndrome, Yin deficiency, Compared with the right coronarysignificant difference (p＜0.05).7. Hemorheology and TCM type: whole blood high and low shear viscosity, plasmaviscosity and whole blood high and Reduction of low shear viscosity and fibrinogen,EAI and other changes in blood flow indices in the sputum, Stasis syndrome havedifferent levels of increased red blood cell deformability in sputum, blood stasis whichhave different degrees of reduction, Sputum with the blockage compared withnon-significant differences (p＜0.05). Sputum Certification Section outstandingperformance in fibrinogen, plasma viscosity of the abnormal increase; Stasis syndromegroup were outstanding performance in the red cell deformability index abnormallower Other indicators of abnormal increase in Phlegm group phase and moreprominent, hematocrit four permits no obvious difference (p＞0.05).8. Dyslipidemia and type of TCM: TC, TG,LDL, and other indicators of abnormallipid metabolism in sputum, Stasis certification varying degrees higher;HDL contrary,in sputum, blood stasis were reduced to varying degrees; Phlegm and which is certifiedand non-certified sputum blockage between non-significant difference (p＜0.05).9. CAG findings and blood rheology changes:9.1 Blood high and low shear viscosity, plasma viscosity and whole blood high andReduction of low shear viscosity and fibrinogen, EAI and other changes in blood flowindicators, Along with coronary artery stenosis severity gradually increased erythrocytedeformability index gradually reduce the contrary. Severe stenosis outstandingperformance in the whole blood high and low shear viscosity and whole blood highand low shear viscosity reduction of the abnormal increase, slightly narrower than witha significant difference (p＜0.05).9.2 With single-vessel disease, the two diseases, multi-vessel disease, high bloodviscosity, whole blood low shear viscosity, plasma viscosity, hematocrit, blood viscosity reduction of high shear, low shear whole blood viscosity reduction,fibrinogen quantitative, EAI gradually increased erythrocyte deformability indexgradually reduced, and the group were not significantly different (p＞0.05).10. CAG with abnormal lipid metabolism of the relationship between:10.1 The group TC, TG; LDL and Lp(a) with an average increase of coronary stenosisand increased and severe stenosis and mild stenosis was significant difference (p＜0.05);the group's average HDL with coronary artery stenosis severity reduced, Severestenosis and mild stenosis there was significant difference (p＜0.05).10.2 With single-vessel, two lesions, multi-vessel disease, TC, TG, gradually rising,However, the group had no significant difference (p＞0.05); LDL group is graduallyrising, But more correlated with single-vessel disease, two disease groups wasstatistically significant (p＜0.05) After between the two was not significant (p＞0.05);the group gradually lowering HDL, the group was no significant difference (p＞0.05);the group Lp (a) between statistical significance (p＜0.05).Conclusions1. Age distribution concentrated mainly in the sand between men than women. Phlegmwhich is certified and 116 (31%); Secondly, blood stasis in 74 cases (19%), phlegmsyndrome in 54 cases (15%), gas stagnation of 30 patients (8%), symptom in 28 cases(8%), Yang-Deficiency Syndrome in 28 cases (8%), the syndrome in 28 cases (8%),tools to permit 6 cases (2%) Yang evidence from 4 cases (1%).2. Coronary artery stenoses in the lighter air stagnation mainly heavier coronary lesionswere compared to Phlegm-card BSP.With increasing degree of stenosis, Phlegmcompatible card, blood stasis, phlegm syndrome, the yin and yang deficiency cardnumber, and reduce air stagnation. Single-vessel coronary artery disease were to airstagnation, blood stasis-based, multi-vessel disease to Phlegm compatible cards,phlegm syndrome, bleeding cards yin, yang deficiency card-based. Multi-vessel disease in the group phase Phlegm and certification significantly more than phlegmsyndrome, blood stasis and Yin deficiency. In a single vessel disease, the park fromcards, certificates tools to significantly less than with stagnation, blood stasis, phlegmsyndrome. TCM-the group total expenditure for coronary artery disease by Yang fromcard to the card to the tools to deficiency of Qi stagnation of the Yin-Yang deficiencyof certification of phlegm syndrome of blood stasis to Phlegm is gradually increasingand certification. The average narrow support from several of the tools to permitcertification of Qi Qi stagnation of the Yang-yang from card to card to the phlegmsyndrome of blood stasis to Phlegm compatible card syndrome in order to increase.With non-sputum-Stasis Syndrome, phlegm syndrome, blood stasis, Phlegm isevidence of coronary Gensini coronary scoring system was used and scores graduallyincreased, blood stasis compatible cards, increased blood stasis phlegm thannon-certified non-obvious blockage. TCM-the coronary lesions with LAD diseaseclosely related to single-vessel disease LAD up, and the existence of coronary lesionsLAD disease is the most; LM simply lesions seen with many other disease. With thelesions increased Phlegm compatible card, blood stasis, phlegm syndrome, thesyndrome in a gradual increase in gas and stagnation. The symptom has declined. Leftcrown lesions main evidence is Phlegm-compatible card, blood stasis, phlegmsyndrome, Yin deficiency, significantly more than the right coronary lesions. Therefore,the CAG findings and TCM.3. Hemorheology and TCM-CAG findings and the relevance Tip: whole blood highand low shear viscosity, plasma viscosity, Whole blood high and low shear viscosityreduction, fibrinogen, EAI and other changes in blood flow indices in the sputum,Stasis syndrome have different levels of increased red blood cell deformability anddifferent degrees. Sputum Certification Section outstanding performance in fibrinogen,plasma viscosity of the abnormal increase; Stasis syndrome group were outstanding performance in the red cell deformability index abnormal lower Other indicators ofabnormal increase in Phlegm group phase and more prominent. Wholeblood high andlow shear viscosity, plasma and whole blood high and low shear viscosity reduction,fibrinogen, EAI changes in blood flow and other indicators, with the degree ofcoronary stenosis severity increased. RBC deformability index will be graduallyreduced. Severe stenosis outstanding performance in the whole blood high and lowshear viscosity and whole blood high and low shear viscosity reduction of theabnormal increase. With single-vessel disease, the two diseases, multi-vessel disease,high blood viscosity, whole blood low shear viscosity, plasma viscosity, hematocrit,Whole blood viscosity reduction of high shear, low shear whole blood viscosityreduction, fibrinogen quantitative, RBC aggregation index gradually increased, RBCdeformability index decreased gradually. Therefore, blood rheology changes TCM andCAG-related results.4. Lipid changes with TCM CAG findings and the relevance Tip: TC, TG, LDL, andother indicators of abnormal lipid metabolism in sputum, blood stasis with varyingdegrees higher;HDL contrary; Phlegm compatible card TC, TG, LDL increasedsignificantly, significantly lower HDL.TC, TG, LDL and Lp(a) with an averageincrease of coronary stenosis and increased; The average HDL with coronary arterystenosis and the lower increase. With single-vessel disease, two lesions, multi-vesseldisease, TC, TG, gradually rising;LDL,Lp(a) is gradually rising, multi-vessel diseasewas significantly higher. Lipid changes TCM and CAG-related results. |
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