| Radix Rosa davurica pall. is the roots after dryness of Rosa davurica pall. Also calls wild rose root. Has the hematischesis and the broad spectrum resist bacteria function, uses in treating the menstruation to continue, functionality and so on uterine hemorrhage, enteritis, bacillary dysentery and nephritis. And sees the root of Rosa davurica pall decoctum enhancement white mouse immunity function report. Has after consults the domestic and foreign literature to be possible to know, the past research concentrated much in to Rosa davurica pall fruit's research, but had Mt. Guanshan to puncture the root the research report to be very few, the pharmacognosy research was the blank.The chemical composition research aspect literature report are extremely few: According to reports, the root of Rosa davurica pall includes the lactone, the tanning substance, the return to original state sugar, the total lucoside, the flavanone, the phenol class, the biological alkalis, the protein, the anthraquinone equi com ponent, moreover ,the total polysaccharide is the even polysaccharide which is composed by the fructose.In 1999, for the first time from puncture the root in the alcohol extraction to sep arate Oleanic acid. And used the double wave length thin layer scanning method to determine the uneven pillar tartaric acid in to puncture in the root ontent.We first from the original plant shape, raw material for medicine shape, the micro distinction, the physics and chemistry distinction and so on several aspects have done the pharmacognosy research.Has made the system pretesting to the chemical composition.And uses the silica gel column chromatographic analysis law and the preparation liquid phase law obtains four monomer compound: Obtains the compound from its Petroleum ether level separationâ… ;The separation obtains the compound from the Chlorform lev elâ…¡,Compoundâ…¢,and compoundâ…£.After chemistry and 1H-NMR, 13C-NMR,GC-MR,UV, IR Spectral analysis instrument synthesis appraisal compoundâ… ,â…¡,â…¢Respectively isβ-Sitosterol, oleanolic acid , ursolic acid; compoundâ…£,The structure is being appraised. Compoundâ… and compoundâ…¢are discovered for the first time from Radix Rosa davurica pall.Through pharmacognosy research and the chemical composition carries on the system to the root of Rosa davurica pall.The research, for expands the new medicine source. establishes raw material for medicine quality evaluation criteria, discussed its active constituent the pharmacological action to lay the foundation. |