Traditional Chinese Medicine Treatment Of Alcoholic Liver Injury In Rats

Objective: Exploration Chinese native medicine compound prescription group side drug efficacy material.Through to three clinical proven prescriptions (Chinese native medicine compound prescription 1.2,3) the research, in 1,2,3 screens from the Chinese native medicine compound prescription to treats the alcoholic liver damage effect good compound prescription, and conducts the thorough research to it, carries on the discussion including its group of side characteristic and to the alcoholic liver damage treatment action mechanism, provides the basis for the clinical medication.Method: Initially sieves the experiment to use the white liquor to plant the mouse for Kunming to fill the stomach 8 weeks to create the alcoholic liver damage model, after the medicine treats 4 weeks to carry on the liver organization pathology inspection as well as the internal organs index observation.Conducts the thorough research to the treatment result good compound prescription.Uses the method which traditional the water decoctum and Shui Jianchun sinks to its effective ingredient to conduct the research.Uses the white liquor to fill the stomach SD big mouse 8 weeks to create the alcoholic liver damage model, after the medicine treats 4 weeks to carry on the liver organization pathology inspection, the internal organs index observation, as well as draws blood with completely automatic biochemistry analyzer examination blood serum liver function enzyme TG, AST, ALT, the GGT change, studies the Chinese native medicine compound prescription the drug efficacy and the effective spot.Through to its whole blood in the ethyl alcohol content determination, GST, NO and NOS, the TNF determination, the selenium element content determination discusses it initially the action mechanism which damages to the alcoholic liver.Result: Initially sieves the experiment to demonstrate that, the Chinese native medicine compound prescription 1.2.3 may the shape change which organizes through the improvement alcoholic liver, but the Chinese native medicine compound prescription 1 water fries the fluid to the mouse which treats the alcoholic liver damage model the Chinese native medicine compound prescription 2 and the Chinese native medicine compound prescription 3 curative effects is better than.The Chinese native medicine compound prescription 1 water fries the fluid, Shui Jianchun sinks the fluid, and Shui Jianchun sinks the supernate damages the function to the alcoholic liver which in the big mouse blood serum TG, AST, ALT, the GGT content has reduces, but the Chinese native medicine compound prescription 1 water fries the fluid the curative effect to fry the Chinese native medicine compound prescription 1 water sinks the supernate function which the fluid and Shui Jianchun sinks to be more remarkable than mellowly.Conclusion: The Chinese native medicine compound prescription 1 water fries the fluid to have the obvious treatment function to the big mouse alcoholic liver damage.