Arterial Pressure To Change The Key Technologies Of The Compliance Of Non-invasive Detection

In modern society, the incidence of cardiovascular disease is high, and it was on an upward trend. Many of cardiovascular diseases are very difficult to cure and are with high mortality and morbidity. The costliness of treatment and rehabilitation often brings patients and their families a heavy burden. Cardiovascular disease is a serious threat to people's lives and health. Atherosclerosis is the pathological basic of cardiovascular disease and plays a very important role in its incidence. Prevention and treatment of cardiovascular disease, the detection of arterial elasticity function is essential.This paper views the compliance of human artery as a variable that changes with the blood pressure. The results can reflect the arterial elastic function more truthfully and objectively. Non-invasive, simple means for the detection of arterial pressure-dependent compliance will be more conducive to large crowds for medical examinations and more conducive to community-oriented prevention of cardiovascular diseases.Arterial pressure-dependent compliance C(p) is the most direct reflection of arterial elasticity. It can not only be qualitative expression on arterial elasticity, but also their quantitative description; can not only reflect a holistic condition of arterial elasticity, but also can reflect compliance change with the arterial blood pressure in detail.In this paper, the main contents are as follows:(1) The establishment and discussion of model for calculating the pressure-dependent compliance C(p). Based on the in-depth study of the human general circulation, this paper establishes the analytic model of general circulation, which includes electrical model and mathematical model. In order to facilitate the practical application of this model, this paper simplifies the model and introduces a simplified analytic model.(2) Noninvasive detection method of human arterial pressure-dependent compliance C(p). Based on the simplifid analytic model, this paper proposes a noninvasive method of pressure-dependent compliance detection. The method acquire the radial artery pressure waveform with the use of piezoelectric sensor. The pressure waveform, after smoothing, single-cycle identification, elimination of the baseline drift, calibration, diastolic identification, and other processes, can be used to calculate the pressure-dependent compliance as the diastolic pressure waveform. Diastolic pressure waveform will be incorporated into the differential equation of the analytic model. An error function err will be defined as the objective function. Searching in a certain range according to a certain step, we can get the best parameters a and b of the pressure-dependent complianceC(p).(3) The experimental system. The major function of the experimental system is data acquisition, control and data analysis. In this paper, the hardware of the experimental system has been introduced. Our focus is on the design of the software.(4) primary experiment, the results and the discussions. Using the experimental system, we carried out a primary experiment. By comparing and analysing the experimental data, this paper verifies the validity and the repeat accuracy of the detection method and the experimental system. Finally, the experimental results are discussed.Our reach is a part of the project "function of the cardiovascular system monitoring technology and equipment", which was subsidized by national 863 plans (Ref: 2006AA02Z4D9).