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Xueshuantong Injection Anti-leukocyte Adhesion In Vitro Experimental Study

Posted on:2008-10-07Degree:MasterType:Thesis
Country:ChinaCandidate:Q WangFull Text:PDF
GTID:2204360212488745Subject:Traditional surgery
Abstract/Summary:PDF Full Text Request
Xueshuantong injection has been widely used in clinical, with blood stasis; Dilated vessels, improve blood circulation, and other functions. Clinically for the treatment of central retinal vein occlusion, stroke sequela, internal ophthalmopathy, Hyphema and other diseases.This Summary covers most of the recent comprehensive collection of Xueshuantong injection of Chinese and Western Medicine,not only in basic research, animal experiments,but also in Clinical research. synthesizing the research results of internal and foreign scholars, this Summary includes four parts : components of Xueshuantong injection, basic pharmacology, to improve blood rheology, Anti-leukocyte adhesion. And this Summary clarifieds the clinical effectiveness and indications of Xueshuantong Injection, and directs us to get better use in clinical in futureIn preliminary vitro-experiments, platelet adhesion NG was used for understanding the physical aspects of leukocyte adhesiveness, high performance liquid chromatogramwas also used to test the PNS concentration in various aqueous solution and leukocyte adhesion rate. We can comprehend the impact of Xueshuantong injection on leukocyte adhesion molecule.Conclusion of preliminary vitro-experiments: the Function of Xueshuantong injection of anti-leukocyte adhesion is better, especially disincentive on cytokine-mediated activation of the adhesion effect, But the Function on endotoxin-mediated adhesion effects is not obvious. Xueshuantong injection has a protective effect on renal ischemia-reperfusion injury in rats.
Keywords/Search Tags:Xueshuantong Injection, Panax Notoginsenosides(PNS), cell adhesion, Pharmacological, Ischemia-reperfusion (IR)
PDF Full Text Request
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