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The Smilax Chemical Composition And Its Resources The Quality Of Research

Posted on:2007-07-01Degree:MasterType:Thesis
Country:ChinaCandidate:S Z XuFull Text:PDF
GTID:2204360185451774Subject:Pharmacy
Abstract/Summary:PDF Full Text Request
Smilax china L.or Jingangteng is a commonly used Chinese medicine, which gathers in "the Chinese Pharmacopoeia" in 2005 version.The dry rhizomex can relieve sickness wet and disintoxication and so on. The Chinese medicine which has the Smilax china L. treat the gynecology department illness, the curative effect is remarkable. The article carried on the plant resources, the chemistry composition, the fingerprints; the content analysis and anti- tumor activeness have conducted the systematic research.The paper investigates the plant resources to 13 provincial capital areas of Smilax china L., gain the distributed characteristic, the ecological environment and it's the reserves information. Thus provide the important reference for the reasonable development used the plant and implemented the GAP planting.The extration and isolation were accompolished with solvent and chromatography method about the Smilax china L. ,got 20 compounds identified 17 compounds.the compound Ergosterot,Gallicacid,Taxifolin,Astibin,Querceetin-3-O-α-L-rha, Proteca-techuic acid and Caffeic acid were disovered for the first time from the Smilax china L.The main effective components of Smilax china L.are Flavanones and the soap glucoside class ingredient, Use the HPLC chromatography to conduct the fingerprint. There were 15 common peaks In the diagram of Flavanones extracting and 4 common peaks In the diagram of Flavanones extracting. The analysis method has good credibility and stability. Thus the quality control standard which connects international rails for this medicinal plant formulation has laid the foundation.Research the content of Smilax china L in different habitat and its 20 kind of close kinships planted by the Diosgenin content. The method is sensitive, simple and accurate, so provide the scientific basis for the GAP planting.Study on the anti- tumor function of differently extracted the spots and compounds by the MTT law. The pharmacology experiment indicated that, the ethyl acetate extracts have the obvious anti- tumor function, and get an effective compound, kaempferol-7-O-β-D-glucoside. It has vital significance to provide the base to discuss the anti- tumor active material.
Keywords/Search Tags:Smilax china L., Resources investigation, Chemical composition, Structure appraisal, Fingerprint, Content analysis, Diosgenin
PDF Full Text Request
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