The Clinical Observation Of Chinese High To Retain The Enema In The Treatment Of Chronic Renal Failure

Objective:To observe the effect of the Traditional Chinese Medicine(TCM) joint treatment (guanchang) on Chronic Renal Failure (CRF). In order to provide the scientific basis for its clinic application. Method:Conforming to the diagnostic standard , the 48 patients were randomly divided into two groups :therapeutic group (n=28), treated with Guanchang; control group (n=20) , treated with Aixite. Other therapeutic methods are the same, such as low-protein diet, positively treating primary dieases,controlling blood pressure and blood sugar, improving microcirculation, applying anti-infective agent, balancing water, electrolyte and PH value, ameliorating anemia. The curative course of both groups were one months. In order to observe the difference of both curative and the changes in the patients before and after treatment in such experiment indexes as Blood Urea Nitrogen(BUN), Serum Creatinine(Scr), Hemoglobin(Hb), Albumin(Alb), Red Blood Cell (RBC), Creatinine clearance rate(Ccr) 24hour urine protein quantity and such symptoms as lassitude in loins, poor appetite , fatigue . Result:1 The total effective rate of the therapeutic group was 82%, higher than the control group 70%, there was no significant difference between two group(P>0.05), which indicated that the therapeutic group had good effect on Chronic renal failure.2 There was significant difference on curative effect in renal function of unfull and recession periods, which indicated that the therapeutic group had better effect on renal function of earlier periods.3 There was no significant difference on curative effect inYang-def iciency of spleen and kidney type, Yin-deficiency of liver and kidney type and deficiency of Yin and Yang type(P>0. 05);while there was significant difference on curative effect in Qi-deficiency of spleen and kidney type between the therapeutic and the control4 groups (P<0. 05), which indicated that the therapeutic group had better effect on Qi-deficiency of spleen and kidney type than the control group. There was significant difference in BUN and Scr between two groups after treatments (P<0. 05), and there was significant different in BUN and Scr between before and behind treatments on both groups (P<0. 05), and the therapeutic group was more evidence (P<0. 01), which indicated that the therapeutic group had better effect on kidney function than the control group.5 There was no significant difference in RBC between before and behind treatments on both groups (P>0. 05), while there was significantdifference in Ccr between before and behind treatments in the therapeutic group(P<0. 01), and there was significant difference in Alb, Hb, 24hupq between before and behind treatments both groups (P<0.05), which indicated that both therapeutic group and control group could increase the signs as Alb, Ccr, 24hupq, Hb, but had no effect in RBC.6 There was no significant difference in improving the symptoms between before and behind treatments of the two groups, especially in the therapeutic group ,which indicated that both therapeutic group and control group could improve the symptoms , and the therapeutic group had better effect than the control group such as poor appetite, nauseated and spitted.Conclusion:After clinical observation , we find Guanchang had good effect onChronic renal failure , it can improve the symptoms and signs, and prolongthe deterioration of kidney function , it has high value , low price inclinic.