The Weikang Granules Pharmacy Part Of The Study

Weikang granules.composed of Pericarpium Citri Reticulatae Viride,Rhizoma Cyperi,Rhizoma coptidis and Cortex Magnoliae Officinalis,etc.,is one of the new traditional Chinese medicine.lt has effieney of dispersing the stagnated Liver-Qi,regulating the function of Spleen, activating Qi and relieving distention and oppression. Weikang Granules is administered in patients of loss of appetite, abdominal distention after eating, stomachache and belching that caused by chronic gastritis. For the sake of clinical application, conjoining the character of medicine, the form of drug was determined granules. After the research of processing, the best technology of processing was contained.then, studies on quality control of it was performed. Rhizoma Coptidis, Fructus Euodiae, Pericarpium Citri Reticulatae Viride and Cortex Magnoliae Officinaliss, were identified by TLC. The content determination of hesperidin has been carried out by reversed-phase HPLC with Cig chemical bonded silica gel as a solid phase, acetonitrile water(19.5:80.5) as a mobile phase and UV detection wavelength at 284nm. The average recovery of the added index was 97.2%(n=6).RSD got by 5 time of determination was 1.8%. The experiment proved that the processing was reasonable and that the method of quality control can be applied. The product markedly inhibits the inflammation caused by the inflammagen.