Chinese Medicine Umbilical Apply The Observation Of The Clinical Efficacy In The Treatment Of Ascites Due To Cirrhosis

Hepatocirrhosis is a common hepatopathy which is a chronic,progressive and diffuse disease by different etiologies, and the ascites is the common and prominent clinical manifestations of decompensated liver cirrhosis, that influences the quality of life seriously.Through literature review and clinical research, the thesis investigated from various angles the understanding,pathogenesis and treatment towards ascites due to cirrhosis of traditional Chinese and western medicine. It investigated the theoretical principle and therapy progress of umbilical application too, and the tentative research and discussion were for better treatment effect towards ascites due to cirrhosis.The literature review has two pieces. The first one is named the research status of the treatment of umbi lical application towards asci tes. It investigated the theoretical principle,the characteristic of Chinese herbs in the umbilical application,the phylogeny of umbilical application and the treatment of umbilical application towards ascites from the traditional Chinese and western medicine, which has disclosed the research status and deficiency. The second one is named the research status of ascites due to cirrhosis. It investigated the etiology,pathogenesis,diagnosis and therapy of ascites due to cirrhosis.Clinical researches:Approach: Use methods of clinical observation basing on stochastic single blind and parallel controlled trial, then divide 48 examples into the treatment group and the control group, which had different treatment method. The control group used the conventional therapy for the ascites due to cirrhosis, the treatment group added umbilical application basing on the treatment of the control group. Record the variation of Symptom score,the weight,the abdominal perimeter,the urinary volume for twenty four hours,the liver function grade,the electrolyte and liver function,the abdominal B ultrasonic inspection, then make the therapeutic evaluation with statistical analysis.Results:In the treatment group total curative effect was 87.5%, and in the control group total curative effect was 62.5%.For both groups in the prior and post treatment, there were significant differences in the symptom scores and the cardinal symptoms that are abdominal distension,hypochondriac pain,oliguria and edema of lower extremity (P<0.05), and the symptom remiss ions in the treatment group were clearly better than that in the control group(P<0.05). In the post treatment, remissions of edema of lower extremity in the treatment group were clearly better than that in the control group (P<0.05), but there were not significant differences in the remissions of abdominal distension,hypochondriac pain and oliguria for both groups (P>0.05). For both groups in the prior and post treatment, there were significant differences in the weight,the abdominal perimeter and the urinary volume for twenty four hours (P<0.01), and remissions in the treatment group were clearly better than that in the control group (P<0.05).For both groups in the prior and post treatment, there were significant differences in the Child-Pugh classification(P<0.01), there weren't significant differences for both groups (P>0.05), but there were significant differences of Child-Pugh scores for both groups (P<0.05), it revealed that the ease of Child-Pugh scores in the treatment group were more than that in the control group. For both groups in the prior and post treatment, there were not significant differences of Na+,Cl-,BUN,Cr(P>0.05), but there were significant differences of K+ (P<0.01). And there were significant differences of K+ in the treatment group (P<0.01),.there were not significant differences of K+ in the control group (P>0.05). In the post treatment, there were significant differences of K+ for both groups (P<0.05). For both groups in the prior and post treatment, there were significant differences in the grade of ascites (P<0.05), and there were significant differences for both groups (P<0.05).Conclusion: It was effective for ascites due to cirrhosis in both groups, but the curative effect of the treatment group was better than the control group obviously, especially in the symptom remissions,hydrouria,the decrease in the abdominal perimeter and weight, the improvement of Child-Pugh scores and potassium ion. So it revealed that the treatment effects of the treatment group were better than the control group, but it needs further studies on the mechanism of action.