| Objective:To investigate and do a research for the relationship between the patinets with phlegm-heat attacking syndrome of CHD and autonomic nervious function of Heart, we have done a study about the difference of Heart rate variability(HRV) by comparing phlegm-heat attacking syndrome and blood-blocked syndrome of CHD.Methods:According to Chinese Medicine Cardiovascular Branch (2007) formulating Guide-line on diagnosis and treatment of Chronic Stable Angina and Guide-line on diagnosis and treatment to non-stable Angina, and non-ST-segmentelevation myocardial infarction, ACC/AHA 2002 guide-line update for the management of patients with unstable angina and non-ST-segmentelevation myocardial infarction, diagnostic standard was formulated. Standard for phlegm-heat attacking syndrome come out, on basis of Treatment on CHD by adjusting function to Spleen and Stomach etc. while diagnosised standard for blood-blocked syndrome baesd on chen ke ji and wang jie etc. It will be devided into Phlegm-heat attacking syndrome and blood-blocked syndrome, after all the patients were diagnosed by TCM Standard. And then, all the patients were be checked with Holter(24h). Finally, the HRV changing characteristics can be analyzed.Results:HRV function sign of Phlegm-heat attacking syndrome of CHD, the result of SDNN and SDANN are lower than that of blood-blocked syndrome. On the contrary, it is the result of RMSSD and PNN50, even though it's not yet remarkable in statistics. To some extent, there may be a stronger function trend in sympathetic nerve of Phlegm-heat attacking syndrome, which plays an important role with parasympathetic nerve in HRV, the same as parasympathetic nerve having a powerful function in Blood-blocked syndrome of CHD.Discuss:HRV has already been applied in clinic, as a steady sign evaluating the function of Automatic Nerve. According to clinic research, there is a possibility that Automatic Nerve refers to a lot of diseases. Especially, when it turns lower, HRV can strongly be a independent risk sector in predicting the death to some of the disease of heart, which is precious in clinic. As for the different TCM syndromes, and relative Automatic Nerve function changing characteristic, we expect that a exploring research can be hold, which can offer some useful information in clinic and improve the Automatic Nerve function of the patients and the general result in CHD. |