The Pathogenesis Of The Syndrome Both Yin And Yang, Divide And Conquer The Treatment Of Liver-fire Insomnia Clinical Studies

To evaluate the clinical efficacy of the treatment based on difference between the treatment of yin and yang on Liver-fire type insomnia with random clinical research method. MethodRandomly divide 49 patients with liver-fire type of insomnia into two groups which the treatment based on difference between the treatment of yin and yang group included 26 patients and the treatment based on syndrome differentiation group included 23 patients. And the first group is the treatment and the second group is the control group. The treatment group patients take the Longdan xiegan decoction one dose per day. At the same time, the treatment group takes the Qi-dimensional blood particles 20mg in the morning and Zaoren liquid sedative 20ml before going to bed. The control group patients take Longdan xiegan decoction one dose per day. The study carries out an investigation and con tradistinction to the two groups using PSQI, Epworth drowsiness scale, and syndrome scale of TCM. Evaluate the clinical efficacy with Pittsburgh Sleep Quality Index(PSQI) and Doctrine Clinical Study of Traditional Chinese New Drug Curing to Insomnia after the 1 week taking the medicine. After collecting the data, record the data, analyze with SPSS 18.0 statistic softy-ware.These 49 cases patients of Liver-fire type insomnia come from the outpatients of Neurology in the Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine from May 2009 to October 2010. The loss account for 5 cases in all cases. The treatment group includes 11 cases of male patients and 13 patients of female patients, the youngest is 20 years old, the largest is 64 years, the mean age is 44.58±9.179 years, the shortest duration is 1 week, the longest is 30 years, the mean disease duration is3.75±6.102 years. The control group there are 9 male patients andll female patients, the youngest is 19 years old and the largest is 62 years old, the mean age is 43.40±12.206 years, the shortest duration is 4 days and the longest is 30 years, the mean disease duration was 3.95±6.798 years.There is comparability of two group of the age, sex, duration level of education, the sleep time, the time required to fall asleep, each item and total score of PSQI and syndrome scale of TCM of the patients, total score of mESS before therapy (P> 0.05). After treatment the two groups, each item and total score of PSQI and syndrome scale of TCM of the patients, total score of mESS all improved. The total effective rate of the both groups is 91.67% and 90%. The total effective rate of sleep quality is 95.83% and 90% in the both groups. The total effective rate of TCM syndrome rates 87.5% in treatment group and 85% in control group (P>0.05). And there were no significance difference comparing with the total clinical effective. The effect of the decrease of the value of the total of PSQI and mESS in the treatment group is better than the one of the control group (P <0.05).(1) The effect on Liver-fire type insomnia by the treatment based on difference between the treatment of yin and yang is same as the one of the treatment based on syndrome differentiation. But the wakefulness and the quality of sleep in the treatment group is better than the one of the control group.(2) The treatment based on difference between the treatment of yin and yang has a clear clinical and theoretical basis and a positive clinical effect. SO it is an effective method for the treatment of insomnia.