| Objective Make assessment on the rheumatoid arthritis'and the depression symptoms in Guiyang City, and study on the relationship between quality of life and depressive symptoms, and on the main influencing factors, all these are on the propose of guiding clinicians for reasonable and effective treatments on the RA patients, and making base for further following study.Method The study is on the hospitalized cases of Rheumatology Division from September in 2008 to February in 2010 in the Second Affiliated Hospital of Traditional Chinese Medicine of Guiyang. The questionnaires included clinical research table of rheumatoid arthritis observation (demographic data, the score of DAS28, etc.), rheumatoid arthritis Quality of Life Scale, Zung Depression Scale. Make a statistical analysis by building the database with SPSS l5.0 software. Main analysis methods: descriptive analysis, difference analysis, linear correlation and multiple regression analysis.Results1. In the 258 cases of RA patients, the highest total score of survival quality is 111, and the lowest is 41, the average score is 75.93±15.28.The worse survival qualities accounted for 45.59%, and the worst accounted for 6.82%. Make the linear correlation analysis on the total score of survival quality and scores in all areas (physical function, psychological function, social function, health self-awareness), and correlation coefficients are 0.806,0.725,0.749,0.766 (P = 0.000).2. In this study, 70.16% of RA patients have depression, of which 34.50% are mild depression, and 27.52% are moderate depression, and 8.14% are severe depression. Make the linear correlation analysis on Depression Scale score and total score of life quality, physical function, psychological function, social function, and self-knowledge of health. The correlation coefficients are 0.63, 0.387, 0.615, 0.504, 0.478 (P = 0.000). To degree depression classification, the total score RA patients survival quality showed an increasing trend (p <0.01).3. the difference was not significant in Total score of survival and depression scale score among patients in different gender, age and duration of RA, and P values were greater than 0.05.however, the result still suggests that the social function of males score higher than females (P = 0.002); 20 to 40-year-old stage of the psychological function of RA patients gets the highest score (P = 0.031) by age group; the course of RA on physical function in patients within 1 year gets the lowest score (P = 0.005) by course group.4. Differences are found between Total score of life quality and depression scale points in various traditional syndromes. Total score of survival quality in alpine blocking collaterals patients is the lowest, while in blood Asthenia patients is the highest. The total score of depression scale in liver-kidney patients is the lowest; while in blood deficiency type patients get the highest points. No significant difference was found in patients with Blockage of damp heat, phlegm paralysis, chills and fever.5. Make a straight line correlation according to the index of disease activity (DAS28 points, CRP, ESR, PLT) and the total score of life quality, and the correlation coefficient is 0.335, 0.375, 0.342, 0.208, sig 0.000, and there is difference from the quality of life scores on all areas, and low relevance with mental function. The disease activity index (DAS28 points, CRP, ESR) and depression scale score were related in low degree, and no relatives between PLT and wireless-related depression scale score. 6. classified according To joint function, RA patients quality of life and depression scale total score ,from low to high , areⅠ<Ⅱ<Ⅲ<Ⅳ. Accompanied by joint effusion or anemia in patients with RA tend to have higher survival total score and the depression scale score, moreover, the correlation coefficient with classification of joint function and total score of survival quality is r = 0.335, sig 0.000, and depression scale score correlation coefficient is r = 0.260, sig 0.000.7. RA patients with RF-positive tend to receive higher survival quality total score, and whether anti-CCP is positive or not has no obvious effect on the total points on survival quality of RA patients. Whether the RF and anti-CCP are positive have no significantly affection on the depression scores of RA patients.8. Multiple regression analysis shows that the degree of depression is the biggest factors in predicted meanings of survival quality total score, and psychological function is the biggest factor in the predicted meaning of depression scale score.Conclusion1. Guiyang urban survival quality of RA patients is threaten badly, in which physiological function is the most serious damage.2. Rheumatoid arthritis with symptoms of depression is in a high proportion.3. No significant difference has found in Survival quality and depressive symptoms of RA patients arrange various genders, ages.4. RA patients with joint effusion or anemia have worse survival quality, and are more likely to be depressed.5. RA patients with depression have worse survival quality, and RA patients with worse mental function are more likely to be depressed.6. It's particularly necessary to emphasize the early aggressive treatment of RA, and much attention should be paid on young patients for psychological intervention treatment, and protect the physiological functions of short-course patients. |
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