Acute Coronary Syndrome Prognostic Risk Factors Analysis

ObjectiveThe aims of the study were to observe acute coronary syndrome (ACS) patients short-term prognosis and to evaluate risk factors associated with clinical prognosis.Methods1. Object choiceStrictly choose 156 patients with acute coronary syndrome who were enrolled as treated group from 2010 Jan to 2011 Feb in our Department of Cardiology on the criterion of bringing and excluding.2. Research design2.1 Record the general clinical features of subjects (age, gender, diagnosis, blood pressure, etc.), past medical history (hypertension, diabetes, dyslipidemia), smoking history and family history. Detect and record the admission electrocardiogram, blood cell analysis, blood lipids, blood glucose and so on.2.2 All patients were followed up for 30 days.Based on the clinical prognosis, ACS patients were divided into four groups:improved group, the death group, non-fatal angina pectoris group, heart failure group.3. Statistics analysisUsing SPSS13.0 software to set up a database and to proceed statistical analysis. quantitative data was described by mean±standard deviation,using analysis of variance between groups; qualitative data was described by rates and proportions, using chi-square test comparison between groups.To make multi-factor analysis by multinomial logistic regression.and to identify risk factors in improved group, the death group, non-fatal angina pectoris group and heart failure group.The elected standard was 0.10, the emission standard was 0.10,calculating OR and 95% CI.. P<0.05 was considered as statistically significant difference.Results1.Risk factors including age, history of diabetes, family history, dyslipidemia, leukocytosis and platelet abnormalities are associated with poor prognosis significantly (P<0.05)2. Logistic regression analysis showed that the independent risk factors of 30-day death included age (OR=1.20,95% CI:1.07～1.34), diabetes (OR=19.41,95% CI:3.02 124.70),leukocytosis (OR=11.36,95% CI:1.87～69.11) and increased platelet (OR=7.72,95% CI:1.29～46.15); the independent risk factors of 30-day angina pectoris included leukocytosis (OR=2.35,95% CI: 0.89～6.17) and dyslipidemia (OR=6.25,95% CI:2.11～18.48); the independent risk factors of 30-day heart failure included age (OR=1.10,95% CI:1.03～1.17), male (OR=4.18,95% CI:0.81～21.51), leukocytosis (OR=2.97,95% CI:1.09～8.14) and dyslipidemia (OR=7.69,95% CI:2.39～24.76).Conclusions1.Age,diabetes,leukocytosis and increased platelet were independent risk factors associated with 30-day death.2. Leukocytosis and dyslipidemia were independent risk factors associated with 30-day angina pectoris.3.Age,male, leukocytosis and dyslipidemia were the independent risk factors associated with 30-day heart failure.